Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity

Sea buckthorn (Hippophae rhamnoides L.) is a natural homologous substance of medicine and food. Polysaccharide, as one of its primary active components, has very superior biological activity and can be used as a dietary supplement for functional foods, with good commercial prospects. Although initia...

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Main Authors: Shuyuan Shi, Ruiyun Wu, Zixin Han, Yu Sun, Pinglan Li, Fazheng Ren, Nan Shang
Format: Article
Language:English
Published: Tsinghua University Press 2025-01-01
Series:Food Science and Human Wellness
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Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250001
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author Shuyuan Shi
Ruiyun Wu
Zixin Han
Yu Sun
Pinglan Li
Fazheng Ren
Nan Shang
author_facet Shuyuan Shi
Ruiyun Wu
Zixin Han
Yu Sun
Pinglan Li
Fazheng Ren
Nan Shang
author_sort Shuyuan Shi
collection DOAJ
description Sea buckthorn (Hippophae rhamnoides L.) is a natural homologous substance of medicine and food. Polysaccharide, as one of its primary active components, has very superior biological activity and can be used as a dietary supplement for functional foods, with good commercial prospects. Although initial progress has been made in the study of sea buckthorn polysaccharides, related studies have been fragmented and lacked systematic and generalization. This manuscript presents a critical analysis and systematic summary of the extraction and purification methods, structural characterization and physicochemical properties, biological activity and potential mechanisms, and structure-activity relationships of sea buckthorn polysaccharides. Accumulating evidence has indicated that sea buckthorn polysaccharides, which were widely prepared by water extraction and column chromatography purifications, exhibited exhibit superior biological activities in vitro and in vivo, including antioxidant, immunomodulatory, anti-inflammatory, hepatorenal protective, antibacterial, antiviral, and prebiotic activities. After analysis, it was concluded that there is a correlation between the relevant activities of sea buckthorn polysaccharides and that the structure of sea buckthorn polysaccharides has a great influence on their biological activity. We reviewed the challenges and limitations of sea buckthorn polysaccharides, summarized the critical aspects, and provided suggestions for potential breakthroughs in the research and application of sea buckthorn polysaccharide.
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issn 2097-0765
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publishDate 2025-01-01
publisher Tsinghua University Press
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spelling doaj-art-99f61ae4fe40455c83ff4a92da8918602025-08-20T02:05:07ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302025-01-01141925000110.26599/FSHW.2024.9250001Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversityShuyuan Shi0Ruiyun Wu1Zixin Han2Yu Sun3Pinglan Li4Fazheng Ren5Nan Shang6Key Laboratory of Precision Nutrition and Food Quality, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Precision Nutrition and Food Quality, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Precision Nutrition and Food Quality, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaKey Laboratory of Precision Nutrition and Food Quality, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Engineering, China Agricultural University, Beijing 100083, ChinaSea buckthorn (Hippophae rhamnoides L.) is a natural homologous substance of medicine and food. Polysaccharide, as one of its primary active components, has very superior biological activity and can be used as a dietary supplement for functional foods, with good commercial prospects. Although initial progress has been made in the study of sea buckthorn polysaccharides, related studies have been fragmented and lacked systematic and generalization. This manuscript presents a critical analysis and systematic summary of the extraction and purification methods, structural characterization and physicochemical properties, biological activity and potential mechanisms, and structure-activity relationships of sea buckthorn polysaccharides. Accumulating evidence has indicated that sea buckthorn polysaccharides, which were widely prepared by water extraction and column chromatography purifications, exhibited exhibit superior biological activities in vitro and in vivo, including antioxidant, immunomodulatory, anti-inflammatory, hepatorenal protective, antibacterial, antiviral, and prebiotic activities. After analysis, it was concluded that there is a correlation between the relevant activities of sea buckthorn polysaccharides and that the structure of sea buckthorn polysaccharides has a great influence on their biological activity. We reviewed the challenges and limitations of sea buckthorn polysaccharides, summarized the critical aspects, and provided suggestions for potential breakthroughs in the research and application of sea buckthorn polysaccharide.https://www.sciopen.com/article/10.26599/FSHW.2024.9250001sea buckthornpolysaccharidespreparationstructural characterizationbioactivities
spellingShingle Shuyuan Shi
Ruiyun Wu
Zixin Han
Yu Sun
Pinglan Li
Fazheng Ren
Nan Shang
Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
Food Science and Human Wellness
sea buckthorn
polysaccharides
preparation
structural characterization
bioactivities
title Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
title_full Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
title_fullStr Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
title_full_unstemmed Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
title_short Prospects of sea buckthorn (Hippophae rhamnoides L.) polysaccharides: preparation, structural characterization, and bioactivities diversity
title_sort prospects of sea buckthorn hippophae rhamnoides l polysaccharides preparation structural characterization and bioactivities diversity
topic sea buckthorn
polysaccharides
preparation
structural characterization
bioactivities
url https://www.sciopen.com/article/10.26599/FSHW.2024.9250001
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