A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon

Abstract Big-barbel schizothorcin (Schizothorax macropogon), an endemic and vulnerable species to the mid-reaches of the Yarlung Zangbo River, epitomizes survival in harsh conditions yet suffers significant population contractions due to human activities. This species was the subject of our study in...

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Main Authors: Xuanguang Liang, Wenhao Wang, Junrou Huang, Mingfei Luo, Nima Wangdui, Caiyun Sun, Jianguo Lu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-024-04266-0
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author Xuanguang Liang
Wenhao Wang
Junrou Huang
Mingfei Luo
Nima Wangdui
Caiyun Sun
Jianguo Lu
author_facet Xuanguang Liang
Wenhao Wang
Junrou Huang
Mingfei Luo
Nima Wangdui
Caiyun Sun
Jianguo Lu
author_sort Xuanguang Liang
collection DOAJ
description Abstract Big-barbel schizothorcin (Schizothorax macropogon), an endemic and vulnerable species to the mid-reaches of the Yarlung Zangbo River, epitomizes survival in harsh conditions yet suffers significant population contractions due to human activities. This species was the subject of our study in which we leveraged PacBio, MGI-Seq, and Hi-C data to assemble a chromosome-scale genome. This assembly comprises 25 pseudo-chromosomes, yielding a genome size of 1.42 Gb with a scaffold N50 length of 59.4 Mb, indicative of a highly contiguous assembly. A BUSCO assessment ascertained the comprehensiveness of the genome at 97.9%. Annotation efforts identified 46,246 putative protein-coding genes, with 49.61% of the assembled genome annotated as repetitive sequences. This genome assembly is instrumental for advancing conservation of the giant whiskered schizothoracines and related species, and for illuminating the evolution and ecology of schizothoracine fishes in the Qinghai-Tibet Plateau.
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spelling doaj-art-99f5a65ce9e849a5947067e19a22ebbf2025-08-20T02:40:21ZengNature PortfolioScientific Data2052-44632024-12-011111810.1038/s41597-024-04266-0A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogonXuanguang Liang0Wenhao Wang1Junrou Huang2Mingfei Luo3Nima Wangdui4Caiyun Sun5Jianguo Lu6School of Marine Sciences, Sun Yat-sen University, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)School of Marine Sciences, Sun Yat-sen University, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)School of Marine Sciences, Sun Yat-sen University, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)Zhuhai Modern Agricultural Development CenterNyingchi agriculture Kema Agriculture Co., LTDNyingchi agriculture Kema Agriculture Co., LTDSchool of Marine Sciences, Sun Yat-sen University, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)Abstract Big-barbel schizothorcin (Schizothorax macropogon), an endemic and vulnerable species to the mid-reaches of the Yarlung Zangbo River, epitomizes survival in harsh conditions yet suffers significant population contractions due to human activities. This species was the subject of our study in which we leveraged PacBio, MGI-Seq, and Hi-C data to assemble a chromosome-scale genome. This assembly comprises 25 pseudo-chromosomes, yielding a genome size of 1.42 Gb with a scaffold N50 length of 59.4 Mb, indicative of a highly contiguous assembly. A BUSCO assessment ascertained the comprehensiveness of the genome at 97.9%. Annotation efforts identified 46,246 putative protein-coding genes, with 49.61% of the assembled genome annotated as repetitive sequences. This genome assembly is instrumental for advancing conservation of the giant whiskered schizothoracines and related species, and for illuminating the evolution and ecology of schizothoracine fishes in the Qinghai-Tibet Plateau.https://doi.org/10.1038/s41597-024-04266-0
spellingShingle Xuanguang Liang
Wenhao Wang
Junrou Huang
Mingfei Luo
Nima Wangdui
Caiyun Sun
Jianguo Lu
A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
Scientific Data
title A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
title_full A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
title_fullStr A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
title_full_unstemmed A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
title_short A chromosome-level genome assembly of big-barbel schizothorcin, Schizothorax macropogon
title_sort chromosome level genome assembly of big barbel schizothorcin schizothorax macropogon
url https://doi.org/10.1038/s41597-024-04266-0
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