The role of HMOX1-mediated ferroptosis in blue light-induced damage to retinal pigment epithelium

The role of HMOX1-mediated ferroptosis in blue light-induced damage to retinal pigment epithelium

Abstract Currently, blue light irradiation is frequently encountered in daily life and is widely considered a high-risk factor for retinal damage. In particular, blue light-induced dysfunction and death of the retinal pigment epithelium (RPE) may ultimately contribute to irreversible vision impairme...

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Bibliographic Details
Main Authors: Chunyi Ji, Yiqi Wang, Yahan Ju, Siwei Liu, Xirui Chen, Jiajing Wang, Na Sun, Zhimin Tang, Ping Gu, Jing Ji
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Ferroptosis
Blue light
HMOX1
Retinal pigment epithelium
Online Access:https://doi.org/10.1038/s41598-025-03757-3
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