RSV infection in Istanbul: risk factors and frequency

Introduction: Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in all age groups especially under two years. The aim of this study was to investigate the frequency and clinical features of RSV in hospitalized children under two years of age with the...

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Main Authors: Elif İzci Güllü, Yasemin Akın, Ayşe Karaaslan, Elif Ruşen Vayvada, Ayşe Ayzıt Atabek, Fatma Kaya Narter
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2017-09-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/8871
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author Elif İzci Güllü
Yasemin Akın
Ayşe Karaaslan
Elif Ruşen Vayvada
Ayşe Ayzıt Atabek
Fatma Kaya Narter
author_facet Elif İzci Güllü
Yasemin Akın
Ayşe Karaaslan
Elif Ruşen Vayvada
Ayşe Ayzıt Atabek
Fatma Kaya Narter
author_sort Elif İzci Güllü
collection DOAJ
description Introduction: Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in all age groups especially under two years. The aim of this study was to investigate the frequency and clinical features of RSV in hospitalized children under two years of age with the diagnosis of lower respiratory tract infections (LRTI) in our region. Methodology: Between September 2011- May 2013, hospitalized children aged 0-2 years with the diagnosis of viral LRTI, in which nasopharengeal secretions  were tested for the presence of the RSV antigen, were included in this prospective study. Results: Among the total of 361 hospitalized children who were investigated for RSV antigen, 138 (38%) were female and 223 (62%) were male. The mean age of the group was 5,7±5,1 months (0-24 months). RSV antigen in nasopharyngeal secretions was positive in 68 (19%) of 361 patients. RSV infection was detected significantly higher in December and January (p = 0.003). RSV positivity was significantly higher in patients aged under 6 months (p=0.01), with shorter duration of breastfeeding (p = 0.02), low socioeconomic status (p = 0.02), and also born with spontaneous vaginal delivery (p = 0.007). In RSV(+) LRTI group, children were associated with severe disease than RSV (- LRTI group (p = 0.014). Conclusions: Since there is lack of data investigating the frequency and the risk factors of RSV respiratory infections in our region, the present study is important for providing new data. Furthermore, this is the second study investigating the correlation between RSV positivity and meteorological conditions in Turkey.
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institution Kabale University
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publishDate 2017-09-01
publisher The Journal of Infection in Developing Countries
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spelling doaj-art-99ec1cf55ad8438ebc6ade09b911e7342025-08-20T03:52:39ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802017-09-01110910.3855/jidc.8871RSV infection in Istanbul: risk factors and frequencyElif İzci Güllü0Yasemin Akın1Ayşe Karaaslan2Elif Ruşen Vayvada3Ayşe Ayzıt Atabek4Fatma Kaya Narter5Dr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, TurkeyDr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, TurkeyDr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, TurkeyDr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, TurkeyDr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, TurkeyDr. Lütfi Kırdar Kartal Education and Research Hospital, Istanbul, Turkey Introduction: Respiratory syncytial virus (RSV) is one of the most common causes of acute respiratory infections in all age groups especially under two years. The aim of this study was to investigate the frequency and clinical features of RSV in hospitalized children under two years of age with the diagnosis of lower respiratory tract infections (LRTI) in our region. Methodology: Between September 2011- May 2013, hospitalized children aged 0-2 years with the diagnosis of viral LRTI, in which nasopharengeal secretions  were tested for the presence of the RSV antigen, were included in this prospective study. Results: Among the total of 361 hospitalized children who were investigated for RSV antigen, 138 (38%) were female and 223 (62%) were male. The mean age of the group was 5,7±5,1 months (0-24 months). RSV antigen in nasopharyngeal secretions was positive in 68 (19%) of 361 patients. RSV infection was detected significantly higher in December and January (p = 0.003). RSV positivity was significantly higher in patients aged under 6 months (p=0.01), with shorter duration of breastfeeding (p = 0.02), low socioeconomic status (p = 0.02), and also born with spontaneous vaginal delivery (p = 0.007). In RSV(+) LRTI group, children were associated with severe disease than RSV (- LRTI group (p = 0.014). Conclusions: Since there is lack of data investigating the frequency and the risk factors of RSV respiratory infections in our region, the present study is important for providing new data. Furthermore, this is the second study investigating the correlation between RSV positivity and meteorological conditions in Turkey. https://jidc.org/index.php/journal/article/view/8871RSVLRTIchildrenrisk factor
spellingShingle Elif İzci Güllü
Yasemin Akın
Ayşe Karaaslan
Elif Ruşen Vayvada
Ayşe Ayzıt Atabek
Fatma Kaya Narter
RSV infection in Istanbul: risk factors and frequency
Journal of Infection in Developing Countries
RSV
LRTI
children
risk factor
title RSV infection in Istanbul: risk factors and frequency
title_full RSV infection in Istanbul: risk factors and frequency
title_fullStr RSV infection in Istanbul: risk factors and frequency
title_full_unstemmed RSV infection in Istanbul: risk factors and frequency
title_short RSV infection in Istanbul: risk factors and frequency
title_sort rsv infection in istanbul risk factors and frequency
topic RSV
LRTI
children
risk factor
url https://jidc.org/index.php/journal/article/view/8871
work_keys_str_mv AT elifizcigullu rsvinfectioninistanbulriskfactorsandfrequency
AT yaseminakın rsvinfectioninistanbulriskfactorsandfrequency
AT aysekaraaslan rsvinfectioninistanbulriskfactorsandfrequency
AT elifrusenvayvada rsvinfectioninistanbulriskfactorsandfrequency
AT ayseayzıtatabek rsvinfectioninistanbulriskfactorsandfrequency
AT fatmakayanarter rsvinfectioninistanbulriskfactorsandfrequency