A posterior cranial fossa lesion mimicking myasthenia gravis
A 41-year-old male with prior diagnosis of seronegative myasthenia gravis presented with complaints of bilateral ptosis, dysphagia, nasal voice and nasal regurgitation. Despite treatment with pyridostigmine, there was lack of significant improvement in the symptoms. Further investigations, including...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2024-11-01
|
| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/5032 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850108190033707008 |
|---|---|
| author | Syed Wajihullah Shah Maryam Khalil Mansoor Iqbal Arham Arif Kundi Muhammad Hassaan |
| author_facet | Syed Wajihullah Shah Maryam Khalil Mansoor Iqbal Arham Arif Kundi Muhammad Hassaan |
| author_sort | Syed Wajihullah Shah |
| collection | DOAJ |
| description | A 41-year-old male with prior diagnosis of seronegative myasthenia gravis presented with complaints of bilateral ptosis, dysphagia, nasal voice and nasal regurgitation. Despite treatment with pyridostigmine, there was lack of significant improvement in the symptoms. Further investigations, including antibody assays and nerve conduction studies did not support the diagnosis. Magnetic resonance imaging revealed a lesion in the posterior cranial fossa, consistent with meningioma, which was compressing surrounding structures. This case highlights the importance of imaging techniques and considering alternative diagnosis in patients with unusual presentations to ensure appropriate management. |
| format | Article |
| id | doaj-art-99ea3ee18c5f44f79586f910f44e5d8f |
| institution | OA Journals |
| issn | 2284-2594 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-99ea3ee18c5f44f79586f910f44e5d8f2025-08-20T02:38:26ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942024-11-0110.12890/2024_0050324567A posterior cranial fossa lesion mimicking myasthenia gravisSyed Wajihullah Shah0https://orcid.org/0009-0008-5215-5772Maryam Khalil1https://orcid.org/0000-0002-3941-875XMansoor Iqbal2https://orcid.org/0000-0001-9282-3183Arham Arif Kundi3https://orcid.org/0000-0003-0707-243XMuhammad Hassaan4Khyber Medical College, Peshawar, PakistanDepartment of Neurology, Pakistan Institute of Medical Sciences, Islamabad, PakistanDepartment of Neurology, Pakistan Institute of Medical Sciences, Islamabad, PakistanKhyber Medical College, Peshawar, PakistanKhyber Medical College, Peshawar, PakistanA 41-year-old male with prior diagnosis of seronegative myasthenia gravis presented with complaints of bilateral ptosis, dysphagia, nasal voice and nasal regurgitation. Despite treatment with pyridostigmine, there was lack of significant improvement in the symptoms. Further investigations, including antibody assays and nerve conduction studies did not support the diagnosis. Magnetic resonance imaging revealed a lesion in the posterior cranial fossa, consistent with meningioma, which was compressing surrounding structures. This case highlights the importance of imaging techniques and considering alternative diagnosis in patients with unusual presentations to ensure appropriate management.https://www.ejcrim.com/index.php/EJCRIM/article/view/5032myasthenia gravisposterior cranial fossaptosismeningiomaneuromuscular junction |
| spellingShingle | Syed Wajihullah Shah Maryam Khalil Mansoor Iqbal Arham Arif Kundi Muhammad Hassaan A posterior cranial fossa lesion mimicking myasthenia gravis European Journal of Case Reports in Internal Medicine myasthenia gravis posterior cranial fossa ptosis meningioma neuromuscular junction |
| title | A posterior cranial fossa lesion mimicking myasthenia gravis |
| title_full | A posterior cranial fossa lesion mimicking myasthenia gravis |
| title_fullStr | A posterior cranial fossa lesion mimicking myasthenia gravis |
| title_full_unstemmed | A posterior cranial fossa lesion mimicking myasthenia gravis |
| title_short | A posterior cranial fossa lesion mimicking myasthenia gravis |
| title_sort | posterior cranial fossa lesion mimicking myasthenia gravis |
| topic | myasthenia gravis posterior cranial fossa ptosis meningioma neuromuscular junction |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/5032 |
| work_keys_str_mv | AT syedwajihullahshah aposteriorcranialfossalesionmimickingmyastheniagravis AT maryamkhalil aposteriorcranialfossalesionmimickingmyastheniagravis AT mansooriqbal aposteriorcranialfossalesionmimickingmyastheniagravis AT arhamarifkundi aposteriorcranialfossalesionmimickingmyastheniagravis AT muhammadhassaan aposteriorcranialfossalesionmimickingmyastheniagravis AT syedwajihullahshah posteriorcranialfossalesionmimickingmyastheniagravis AT maryamkhalil posteriorcranialfossalesionmimickingmyastheniagravis AT mansooriqbal posteriorcranialfossalesionmimickingmyastheniagravis AT arhamarifkundi posteriorcranialfossalesionmimickingmyastheniagravis AT muhammadhassaan posteriorcranialfossalesionmimickingmyastheniagravis |