Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis
The goal was to know about the anthelmintic properties of the leaves of P. americana and peels of M. sikkimensis. An ethanolic extract from the leaves of P. americana and aqueous extract of M. sikkimensis was used to screen for phytochemicals and analyse the anthelmintic activity on Indian...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Krupanidhi College of Pharmacy
2024-06-01
|
| Series: | Journal of Pharmaceutical Research |
| Online Access: | https://jopcr.com/articles/evaluation-of-anthelmintic-activities-of-persea-americana-and-musa-sikkimensis |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849230174316396544 |
|---|---|
| author | Nihar Ranjan Sarmah Preety Rani Gupta Raksha Sharma Tashi Narbu Moktan Ananya Bhattacharjee |
| author_facet | Nihar Ranjan Sarmah Preety Rani Gupta Raksha Sharma Tashi Narbu Moktan Ananya Bhattacharjee |
| author_sort | Nihar Ranjan Sarmah |
| collection | DOAJ |
| description | The goal was to know about the anthelmintic properties of the leaves of P. americana and peels of M. sikkimensis. An ethanolic extract from the leaves of P. americana and aqueous extract of M. sikkimensis was used to screen for phytochemicals and analyse the anthelmintic activity on Indian earthworm Pheretima posthuma to determine its therapeutic capabilities. The experiment was carried out by preparing standard drug solution (Albendazole), P. americana leaf extract and M. sikkimensis peel extract in a concentration range of 5mg/ml, 10mg/ml and 20mg/ml respectively for each. The earthworms were placed in a beaker with solutions of varying concentrations. The time of paralysis and death was noted and plotted in a graph. From the results, it was found that P. americana and M. sikkimensis extract caused paralysis in less time in a dose-dependent manner, as well as the death was caused much earlier compared to the control group. This suggests that P. americana and M. sikkimensis extract exhibited strong anthelmintic activity. Furthermore, a link has been found between anthelmintic activity and high levels of flavonoids, terpenoids and tannins. Flavonoids, tannins and terpenoids found in various extracts have been proven to have anthelmintic properties in earlier investigations. Persea americana have been reported to have alkaloids, flavonoids, glycosides, saponins, steroids, tannins, proteins, and Musa sikkimensis have been reported to have alkaloids, glycosides, saponins, steroids, terpenoids, tannins, proteins. These results lead to the conclusion that P. americana and M. sikkimensis extract may possess anthelmintic activity. Keywords: Anthelmintic activity, Helminth, Musa, Avocado |
| format | Article |
| id | doaj-art-99da9d801e1e4620aad0c87ecd53bc36 |
| institution | Kabale University |
| issn | 0973-7200 2454-8405 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Krupanidhi College of Pharmacy |
| record_format | Article |
| series | Journal of Pharmaceutical Research |
| spelling | doaj-art-99da9d801e1e4620aad0c87ecd53bc362025-08-21T09:34:09ZengKrupanidhi College of PharmacyJournal of Pharmaceutical Research0973-72002454-84052024-06-0123211912310.18579/jopcr/v23.2.59Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensisNihar Ranjan SarmahPreety Rani GuptaRaksha SharmaTashi Narbu MoktanAnanya Bhattacharjee The goal was to know about the anthelmintic properties of the leaves of P. americana and peels of M. sikkimensis. An ethanolic extract from the leaves of P. americana and aqueous extract of M. sikkimensis was used to screen for phytochemicals and analyse the anthelmintic activity on Indian earthworm Pheretima posthuma to determine its therapeutic capabilities. The experiment was carried out by preparing standard drug solution (Albendazole), P. americana leaf extract and M. sikkimensis peel extract in a concentration range of 5mg/ml, 10mg/ml and 20mg/ml respectively for each. The earthworms were placed in a beaker with solutions of varying concentrations. The time of paralysis and death was noted and plotted in a graph. From the results, it was found that P. americana and M. sikkimensis extract caused paralysis in less time in a dose-dependent manner, as well as the death was caused much earlier compared to the control group. This suggests that P. americana and M. sikkimensis extract exhibited strong anthelmintic activity. Furthermore, a link has been found between anthelmintic activity and high levels of flavonoids, terpenoids and tannins. Flavonoids, tannins and terpenoids found in various extracts have been proven to have anthelmintic properties in earlier investigations. Persea americana have been reported to have alkaloids, flavonoids, glycosides, saponins, steroids, tannins, proteins, and Musa sikkimensis have been reported to have alkaloids, glycosides, saponins, steroids, terpenoids, tannins, proteins. These results lead to the conclusion that P. americana and M. sikkimensis extract may possess anthelmintic activity. Keywords: Anthelmintic activity, Helminth, Musa, Avocadohttps://jopcr.com/articles/evaluation-of-anthelmintic-activities-of-persea-americana-and-musa-sikkimensis |
| spellingShingle | Nihar Ranjan Sarmah Preety Rani Gupta Raksha Sharma Tashi Narbu Moktan Ananya Bhattacharjee Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis Journal of Pharmaceutical Research |
| title | Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis |
| title_full | Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis |
| title_fullStr | Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis |
| title_full_unstemmed | Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis |
| title_short | Evaluation of Anthelmintic Activities of Persea americana and Musa sikkimensis |
| title_sort | evaluation of anthelmintic activities of persea americana and musa sikkimensis |
| url | https://jopcr.com/articles/evaluation-of-anthelmintic-activities-of-persea-americana-and-musa-sikkimensis |
| work_keys_str_mv | AT niharranjansarmah evaluationofanthelminticactivitiesofperseaamericanaandmusasikkimensis AT preetyranigupta evaluationofanthelminticactivitiesofperseaamericanaandmusasikkimensis AT rakshasharma evaluationofanthelminticactivitiesofperseaamericanaandmusasikkimensis AT tashinarbumoktan evaluationofanthelminticactivitiesofperseaamericanaandmusasikkimensis AT ananyabhattacharjee evaluationofanthelminticactivitiesofperseaamericanaandmusasikkimensis |