The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region

Purpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12...

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Main Authors: O. L. Kireeva, O. V. Chlebnikova, S. S. Amelina, G. I. Elchinova, R. A. Zinchenko, V. V. Kadsjyshev, E. K. Ginter
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/166
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author O. L. Kireeva
O. V. Chlebnikova
S. S. Amelina
G. I. Elchinova
R. A. Zinchenko
V. V. Kadsjyshev
E. K. Ginter
author_facet O. L. Kireeva
O. V. Chlebnikova
S. S. Amelina
G. I. Elchinova
R. A. Zinchenko
V. V. Kadsjyshev
E. K. Ginter
author_sort O. L. Kireeva
collection DOAJ
description Purpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12 districts of the region — 497460 people, including 97345 children (0-18 years). Regardless of age for the selection of patients used the original protocol of genetic-epidemiological studies, developed over 30 years ago, in Genetic Epidemiology Labora- tory Medical Genetic Research Center.Results: In the group of the child population identified 84 patients from 72 families. the most commonly diagnosed congenital cataract various forms (36.1%), congenital horizontal nystagmus (18.0%), monogenic defects eyes (15.6%), congenital ptosis (15.6%), hereditary retinal dystrophy (9, 6%). the overall prevalence of hereditary eye diseases among the adult population was 2.42±0.25, children 8.63±0.94 to 10,000 people.Conclusion: Conducting genetic epidemiology studies will improve eye health and medical genetic care.
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institution Kabale University
issn 1816-5095
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publishDate 2014-07-01
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record_format Article
series Oftalʹmologiâ
spelling doaj-art-99d86c97413a4bda837effa2f75ea9b32025-08-20T03:38:01ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-019481310.18008/1816-5095-2012-4-8-13166The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov regionO. L. Kireeva0O. V. Chlebnikova1S. S. Amelina2G. I. Elchinova3R. A. Zinchenko4V. V. Kadsjyshev5E. K. Ginter6Медико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваРостовская областная клиническая больница, Ростов-на-ДонуМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваPurpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12 districts of the region — 497460 people, including 97345 children (0-18 years). Regardless of age for the selection of patients used the original protocol of genetic-epidemiological studies, developed over 30 years ago, in Genetic Epidemiology Labora- tory Medical Genetic Research Center.Results: In the group of the child population identified 84 patients from 72 families. the most commonly diagnosed congenital cataract various forms (36.1%), congenital horizontal nystagmus (18.0%), monogenic defects eyes (15.6%), congenital ptosis (15.6%), hereditary retinal dystrophy (9, 6%). the overall prevalence of hereditary eye diseases among the adult population was 2.42±0.25, children 8.63±0.94 to 10,000 people.Conclusion: Conducting genetic epidemiology studies will improve eye health and medical genetic care.https://www.ophthalmojournal.com/opht/article/view/166hereditary ophthalmopathologythe prevalence of hereditary diseasesthe clinical polymorphism
spellingShingle O. L. Kireeva
O. V. Chlebnikova
S. S. Amelina
G. I. Elchinova
R. A. Zinchenko
V. V. Kadsjyshev
E. K. Ginter
The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
Oftalʹmologiâ
hereditary ophthalmopathology
the prevalence of hereditary diseases
the clinical polymorphism
title The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
title_full The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
title_fullStr The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
title_full_unstemmed The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
title_short The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
title_sort clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the rostov region
topic hereditary ophthalmopathology
the prevalence of hereditary diseases
the clinical polymorphism
url https://www.ophthalmojournal.com/opht/article/view/166
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