Hexameric-Based Hierarchy in the Sizes of a Cytolysin Pore-Forming Complex

Perfringolysin O (PFO) is a prototypical member of a large family of pore-forming toxins (PFTs) that are potent virulence factors for many pathogenic bacteria. One of the most enigmatic properties of these PFTs is how structural changes are coordinated between different subunits within a single comp...

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Bibliographic Details
Main Authors: Meijun Liu, Xintao Qin, Menglin Luo, Yi Shen, Jiabin Wang, Jielin Sun, Daniel M. Czajkowsky, Zhifeng Shao
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/15/3/424
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