THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS

It is well known that the inflammatory process in rheumatoid arthritis (RA) is mediated by free radicals. Antioxidant vitamins can neutralize oxidative cell damage, so they suggested alleviate symptoms and prevent progression of RA. This article provides an overview of a current literature about cli...

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Main Authors: Zh. V. Maximova, D. M. Maximov
Format: Article
Language:Russian
Published: SINAPS LLC 2017-05-01
Series:Архивъ внутренней медицины
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Online Access:https://www.medarhive.ru/jour/article/view/652
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author Zh. V. Maximova
D. M. Maximov
author_facet Zh. V. Maximova
D. M. Maximov
author_sort Zh. V. Maximova
collection DOAJ
description It is well known that the inflammatory process in rheumatoid arthritis (RA) is mediated by free radicals. Antioxidant vitamins can neutralize oxidative cell damage, so they suggested alleviate symptoms and prevent progression of RA. This article provides an overview of a current literature about clinical role of the antioxidant vitamins in patients with RA. In general, only a few clinical trials focused on this issue, and just a high dose vitamin E supplementation demonstrated moderate clinical efficacy in RA. On the other hand, convincing evidence exist that Mediterranean diet, rich in antioxidants, may reduce inflammatory activity, increase physical functioning and improve general well-being. In conclusion, patients with RA should follow antioxidant-rich diet (grains, fruits, vegetables) rather than take vitamin supplementation.
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spelling doaj-art-99d55e059a4b454c92b9ff3400d0ff1e2025-08-20T03:37:57ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642017-05-017318118710.20514/2226-6704-2017-7-3-181-187595THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITISZh. V. Maximova0D. M. Maximov1Ural State Medical University, EkaterinburgUral State Medical University, EkaterinburgIt is well known that the inflammatory process in rheumatoid arthritis (RA) is mediated by free radicals. Antioxidant vitamins can neutralize oxidative cell damage, so they suggested alleviate symptoms and prevent progression of RA. This article provides an overview of a current literature about clinical role of the antioxidant vitamins in patients with RA. In general, only a few clinical trials focused on this issue, and just a high dose vitamin E supplementation demonstrated moderate clinical efficacy in RA. On the other hand, convincing evidence exist that Mediterranean diet, rich in antioxidants, may reduce inflammatory activity, increase physical functioning and improve general well-being. In conclusion, patients with RA should follow antioxidant-rich diet (grains, fruits, vegetables) rather than take vitamin supplementation.https://www.medarhive.ru/jour/article/view/652vitaminsantioxidantsrheumatoid arthritistreatment
spellingShingle Zh. V. Maximova
D. M. Maximov
THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
Архивъ внутренней медицины
vitamins
antioxidants
rheumatoid arthritis
treatment
title THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
title_full THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
title_fullStr THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
title_full_unstemmed THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
title_short THE ROLE OF VITAMINS IN THE TREATMENT OF RHEUMATOID ARTHRITIS
title_sort role of vitamins in the treatment of rheumatoid arthritis
topic vitamins
antioxidants
rheumatoid arthritis
treatment
url https://www.medarhive.ru/jour/article/view/652
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