Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study
Background Global Asthma Network (GAN) was established in 2012 as a development to the International Study of Asthma and Allergies in Childhood to improve asthma care globally.Objective To survey asthma, allergic rhinitis and atopic dermatitis in primary and secondary school children and to investig...
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BMJ Publishing Group
2020-09-01
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| Series: | BMJ Open Respiratory Research |
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| author | Philippa Ellwood Luis Garcia-Marcos Blanca Estela Del-Río-Navarro Arturo Berber Nayely Reyes-Noriega Elsy Maureen Navarrete-Rodríguez Roberto García-Almaraz Omar Josué Saucedo-Ramírez Valente Juan Mérida-Palacio Beatriz Del Carmen Ramos-García Alberto José Escalante-Domínguez Francisco Javier Linares-Zapién Héctor Leonardo Moreno-Gardea Georgina Ochoa-López Luis Octavio Hernández-Mondragón José Santos Lozano-Sáenz José Antonio Sacre-Hazouri Ángeles Juan-Pineda Ma Guadalupe Sánchez-Coronel Noel Rodríguez-Pérez María de Jesús Ambriz-Moreno OJ Saucedo Ramírez V Merida-Palacio BC Ramos-García AJ Escalante-Dominguez F Linares-Zapien HL Gardea-Moreno G Ochoa-Lopez LO Hernández-Mondragón JS Lozano-Saenz JA Sacre-Hazouri A Juan-Pineda MG Sánchez Coronel N Rodríguez-Pérez MJ Ambriz-Moreno |
| author_facet | Philippa Ellwood Luis Garcia-Marcos Blanca Estela Del-Río-Navarro Arturo Berber Nayely Reyes-Noriega Elsy Maureen Navarrete-Rodríguez Roberto García-Almaraz Omar Josué Saucedo-Ramírez Valente Juan Mérida-Palacio Beatriz Del Carmen Ramos-García Alberto José Escalante-Domínguez Francisco Javier Linares-Zapién Héctor Leonardo Moreno-Gardea Georgina Ochoa-López Luis Octavio Hernández-Mondragón José Santos Lozano-Sáenz José Antonio Sacre-Hazouri Ángeles Juan-Pineda Ma Guadalupe Sánchez-Coronel Noel Rodríguez-Pérez María de Jesús Ambriz-Moreno OJ Saucedo Ramírez V Merida-Palacio BC Ramos-García AJ Escalante-Dominguez F Linares-Zapien HL Gardea-Moreno G Ochoa-Lopez LO Hernández-Mondragón JS Lozano-Saenz JA Sacre-Hazouri A Juan-Pineda MG Sánchez Coronel N Rodríguez-Pérez MJ Ambriz-Moreno |
| author_sort | Philippa Ellwood |
| collection | DOAJ |
| description | Background Global Asthma Network (GAN) was established in 2012 as a development to the International Study of Asthma and Allergies in Childhood to improve asthma care globally.Objective To survey asthma, allergic rhinitis and atopic dermatitis in primary and secondary school children and to investigate and evaluate its prevalence, severity, management and risk factors in Mexico.Methods GAN Phase I is a cross-sectional, multicentre survey carried out in 15 centres corresponding to 14 Mexican cities throughout 2016–2019 using the validated Spanish language version of the GAN Phase I questionnaires. The questionnaires were completed by parents of 6–7-year-old primary school pupils (school children) and by 13–14-year-old adolescents.Results A total of 35 780 school children and 41 399 adolescents participated. Wheezing ever prevalence was 26.2% (95% CI 25.8% to 26.7%) in school children and 23.9% (95% CI 23.4% to 24.3%) in adolescents. The corresponding frequencies for current wheeze were 10.2% (95% CI 9.9% to 10.5%) and 11.6% (95% CI 11.2% to 11.9%). In school children, the risk factors for current wheeze were rhinitis (OR 4.484; 95% CI 3.915% to 5.134%) and rash symptoms (OR 1.735; 95% CI 1.461% to 2.059%). For adolescents, rhinitis symptoms (OR 3.492; 95% CI 3.188% to 3.825%) and allergic rhinitis diagnosis (OR 2.144; 95% CI 1.787% to 2.572%) were the most significant. For both groups, there was a negative relation with centres’ sea level altitude higher than 1500 m above mean sea level (p<0.005).Conclusions The most important risk factors for asthma symptoms in both age groups were the presence of rhinitis and rash symptoms or diagnosis. On the other hand, sea level altitude higher than 1500 metres was a protective factor. |
| format | Article |
| id | doaj-art-99d39977bce04ffb9e24c8fd2e4d1476 |
| institution | OA Journals |
| issn | 2052-4439 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open Respiratory Research |
| spelling | doaj-art-99d39977bce04ffb9e24c8fd2e4d14762025-08-20T02:33:32ZengBMJ Publishing GroupBMJ Open Respiratory Research2052-44392020-09-017110.1136/bmjresp-2020-000658Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional studyPhilippa Ellwood0Luis Garcia-Marcos1Blanca Estela Del-Río-Navarro2Arturo Berber3Nayely Reyes-Noriega4Elsy Maureen Navarrete-Rodríguez5Roberto García-Almaraz6Omar Josué Saucedo-Ramírez7Valente Juan Mérida-Palacio8Beatriz Del Carmen Ramos-García9Alberto José Escalante-Domínguez10Francisco Javier Linares-Zapién11Héctor Leonardo Moreno-Gardea12Georgina Ochoa-López13Luis Octavio Hernández-Mondragón14José Santos Lozano-Sáenz15José Antonio Sacre-Hazouri16Ángeles Juan-Pineda17Ma Guadalupe Sánchez-Coronel18Noel Rodríguez-Pérez19María de Jesús Ambriz-Moreno20OJ Saucedo RamírezV Merida-PalacioBC Ramos-GarcíaAJ Escalante-DominguezF Linares-ZapienHL Gardea-MorenoG Ochoa-LopezLO Hernández-MondragónJS Lozano-SaenzJA Sacre-HazouriA Juan-PinedaMG Sánchez CoronelN Rodríguez-PérezMJ Ambriz-MorenoPaediatrics: Child and Youth Health, The University of Auckland, Auckland, New ZealandPaediatric Allergy and Pulmonology Units ‘Virgen de la Arrixaca’ University Children’s Hospital, University of Murcia, Universidad de Murcia, Murcia, SpainAllergy and Immunology, Hospital Infantil de México Federico Gomez, Mexico City, MexicoAllergy and Immunology, Hospital Infantil de México Federico Gomez, Mexico City, MexicoAllergy and Immunology, Hospital Infantil de México Federico Gomez, Mexico City, MexicoAllergy and Immunology, Hospital Infantil de México Federico Gomez, Mexico City, MexicoAllergy and Immunology, Hospital Infantil de Tamaulipas, Ciudad Victoria, MexicoAllergy and Immunology, Hospital Infantil de México Federico Gomez, Mexico City, MexicoAllergy and Immunology, Clínica de Asma-Alergia, Mexicali, MexicoAllergy and Immunology, Instituto Mexicano del Seguro Social, San Luis Potosí, San Luis Potosí, MexicoAllergy and Immunology, Hospital General de Tijuana, Tijuana, MexicoAllergy and Immunology, Centro de Investigación, Diagnóstico y Tratamiento de Asma y Alergias, Toluca, Estado de México, MexicoAllergy and Immunology, Hospital Ángeles Chihuahua, Chihuahua, MexicoAllergy and Immunology, Hospital Ángeles Ciudad Juárez, Chihuahua, MexicoAllergy and Immunology, CRIT Michoacán, Morelia, Michoacán, MexicoAllergy and Immunology, Hospital Ángeles Xalapa, Xalapa, Veracruz, MexicoAllergy and Immunology, Universidad Veracruzana, Córdoba, Veracruz, MexicoAllergy and Immunology, Private practice, Puerto Vallarta, Jalisco, MexicoAllergy and Immunology, Benemérita Universidad Autónoma de Aguascalientes, Aguascalientes, MexicoAllergy and Immunology, Benemérita Universidad Autónoma de Aguascalientes, Aguascalientes, MexicoAllergy and Immunology, Hospital General de Matamoros, Matamoros, MexicoBackground Global Asthma Network (GAN) was established in 2012 as a development to the International Study of Asthma and Allergies in Childhood to improve asthma care globally.Objective To survey asthma, allergic rhinitis and atopic dermatitis in primary and secondary school children and to investigate and evaluate its prevalence, severity, management and risk factors in Mexico.Methods GAN Phase I is a cross-sectional, multicentre survey carried out in 15 centres corresponding to 14 Mexican cities throughout 2016–2019 using the validated Spanish language version of the GAN Phase I questionnaires. The questionnaires were completed by parents of 6–7-year-old primary school pupils (school children) and by 13–14-year-old adolescents.Results A total of 35 780 school children and 41 399 adolescents participated. Wheezing ever prevalence was 26.2% (95% CI 25.8% to 26.7%) in school children and 23.9% (95% CI 23.4% to 24.3%) in adolescents. The corresponding frequencies for current wheeze were 10.2% (95% CI 9.9% to 10.5%) and 11.6% (95% CI 11.2% to 11.9%). In school children, the risk factors for current wheeze were rhinitis (OR 4.484; 95% CI 3.915% to 5.134%) and rash symptoms (OR 1.735; 95% CI 1.461% to 2.059%). For adolescents, rhinitis symptoms (OR 3.492; 95% CI 3.188% to 3.825%) and allergic rhinitis diagnosis (OR 2.144; 95% CI 1.787% to 2.572%) were the most significant. For both groups, there was a negative relation with centres’ sea level altitude higher than 1500 m above mean sea level (p<0.005).Conclusions The most important risk factors for asthma symptoms in both age groups were the presence of rhinitis and rash symptoms or diagnosis. On the other hand, sea level altitude higher than 1500 metres was a protective factor.https://bmjopenrespres.bmj.com/content/7/1/e000658.full |
| spellingShingle | Philippa Ellwood Luis Garcia-Marcos Blanca Estela Del-Río-Navarro Arturo Berber Nayely Reyes-Noriega Elsy Maureen Navarrete-Rodríguez Roberto García-Almaraz Omar Josué Saucedo-Ramírez Valente Juan Mérida-Palacio Beatriz Del Carmen Ramos-García Alberto José Escalante-Domínguez Francisco Javier Linares-Zapién Héctor Leonardo Moreno-Gardea Georgina Ochoa-López Luis Octavio Hernández-Mondragón José Santos Lozano-Sáenz José Antonio Sacre-Hazouri Ángeles Juan-Pineda Ma Guadalupe Sánchez-Coronel Noel Rodríguez-Pérez María de Jesús Ambriz-Moreno OJ Saucedo Ramírez V Merida-Palacio BC Ramos-García AJ Escalante-Dominguez F Linares-Zapien HL Gardea-Moreno G Ochoa-Lopez LO Hernández-Mondragón JS Lozano-Saenz JA Sacre-Hazouri A Juan-Pineda MG Sánchez Coronel N Rodríguez-Pérez MJ Ambriz-Moreno Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study BMJ Open Respiratory Research |
| title | Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study |
| title_full | Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study |
| title_fullStr | Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study |
| title_full_unstemmed | Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study |
| title_short | Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study |
| title_sort | global asthma network phase i study in mexico prevalence of asthma symptoms risk factors and altitude associations a cross sectional study |
| url | https://bmjopenrespres.bmj.com/content/7/1/e000658.full |
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