Mixture tetracycline citric acid and detergent – A root canal irrigant. A review

Background: Root canal irrigants play an indispensable role for the complete disinfection of the root canal system, in particular those areas of the root canal that are not accessible for instrumentation. Sodium hypochlorite, ethylene diamine tetra acetic acid, hydrogen peroxide and chlorhexidine ar...

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Main Authors: G.P.V. Srikumar, K.S. Sekhar, K.G. Nischith
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Oral Biology and Craniofacial Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212426812000486
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author G.P.V. Srikumar
K.S. Sekhar
K.G. Nischith
author_facet G.P.V. Srikumar
K.S. Sekhar
K.G. Nischith
author_sort G.P.V. Srikumar
collection DOAJ
description Background: Root canal irrigants play an indispensable role for the complete disinfection of the root canal system, in particular those areas of the root canal that are not accessible for instrumentation. Sodium hypochlorite, ethylene diamine tetra acetic acid, hydrogen peroxide and chlorhexidine are the most commonly used root canal irrigants in endodontic practice, but they do not satisfy all the properties of an ideal root canal irrigant. Mixture tetracycline, citric acid and detergent, a root canal irrigant, is commercially available as BioPure MTAD (Dentsply, Tulsa Dental, Tulsa, OK). Methodology: The literature was searched for root canal irrigants used in the last 3 decades in PubMed. Data showed 83 relevant articles, of which 24 were found most suitable on the basis of description of properties, advantages and disadvantages of MTAD, hence were included. The aim of this study was to evaluate the properties of MTAD for its antibacterial efficiency, biocompatibility, chelating action with removal of endodontic smear layer and compare it with other commonly used root canal irrigants like sodium hypochlorite, ethylene diamine tetra acetic acid, hydrogen peroxide, chlorhexidine. Results: MTAD was found to be highly effective intracanal irrigant compared to other commonly used root canal irrigants with excellent disinfection of the entire root canal system. Conclusion: MTAD is biocompatible with superior antimicrobial efficiency compared to other commonly used root canal irrigants.
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spelling doaj-art-99c7d2cbdc69432db85826384c24747d2025-08-20T02:01:57ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682013-01-0131313510.1016/j.jobcr.2012.09.001Mixture tetracycline citric acid and detergent – A root canal irrigant. A reviewG.P.V. Srikumar0K.S. Sekhar1K.G. Nischith2Senior Lecturer, Department of Conservative Dentistry & Endodontics, Purvanchal Institute of Dental Sciences, GIDA, Gorakhpur, Uttar Pradesh, India; Corresponding author. Door No: 50-LIG-I-123 – Upstairs, A.P. Housing Board Colony, B – Camp Last, Kurnool 518002, Andhra Pradesh, India. Tel.: +91 9956064727, +91 9989113077.Principal and HOD, Department of Conservative Dentistry & Endodontics, Purvanchal Institute of Dental Sciences, GIDA, Gorakhpur, Uttar Pradesh, IndiaProfessor & HOD, Department of Conservative Dentistry & Endodontics, Malabar Dental College, Kuttippuram, Kerala, IndiaBackground: Root canal irrigants play an indispensable role for the complete disinfection of the root canal system, in particular those areas of the root canal that are not accessible for instrumentation. Sodium hypochlorite, ethylene diamine tetra acetic acid, hydrogen peroxide and chlorhexidine are the most commonly used root canal irrigants in endodontic practice, but they do not satisfy all the properties of an ideal root canal irrigant. Mixture tetracycline, citric acid and detergent, a root canal irrigant, is commercially available as BioPure MTAD (Dentsply, Tulsa Dental, Tulsa, OK). Methodology: The literature was searched for root canal irrigants used in the last 3 decades in PubMed. Data showed 83 relevant articles, of which 24 were found most suitable on the basis of description of properties, advantages and disadvantages of MTAD, hence were included. The aim of this study was to evaluate the properties of MTAD for its antibacterial efficiency, biocompatibility, chelating action with removal of endodontic smear layer and compare it with other commonly used root canal irrigants like sodium hypochlorite, ethylene diamine tetra acetic acid, hydrogen peroxide, chlorhexidine. Results: MTAD was found to be highly effective intracanal irrigant compared to other commonly used root canal irrigants with excellent disinfection of the entire root canal system. Conclusion: MTAD is biocompatible with superior antimicrobial efficiency compared to other commonly used root canal irrigants.http://www.sciencedirect.com/science/article/pii/S2212426812000486MTADSodium hypochlorite (NaOCl)Ethylene diamine tetra acetic acid (EDTA)Hydrogen peroxideRoot/intra canal irrigants
spellingShingle G.P.V. Srikumar
K.S. Sekhar
K.G. Nischith
Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
Journal of Oral Biology and Craniofacial Research
MTAD
Sodium hypochlorite (NaOCl)
Ethylene diamine tetra acetic acid (EDTA)
Hydrogen peroxide
Root/intra canal irrigants
title Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
title_full Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
title_fullStr Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
title_full_unstemmed Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
title_short Mixture tetracycline citric acid and detergent – A root canal irrigant. A review
title_sort mixture tetracycline citric acid and detergent a root canal irrigant a review
topic MTAD
Sodium hypochlorite (NaOCl)
Ethylene diamine tetra acetic acid (EDTA)
Hydrogen peroxide
Root/intra canal irrigants
url http://www.sciencedirect.com/science/article/pii/S2212426812000486
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