Treatment of Advanced Parkinson's Disease
Patients at late stage Parkinson's disease (PD) develop several motor and nonmotor complications, which dramatically impair their quality of life. These complications include motor fluctuations, dyskinesia, unpredictable or absent response to medications, falls, dysautonomia, dementia, hallucin...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.4061/2010/480260 |
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| _version_ | 1832552031512952832 |
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| author | Sara Varanese Zoe Birnbaum Roger Rossi Alessandro Di Rocco |
| author_facet | Sara Varanese Zoe Birnbaum Roger Rossi Alessandro Di Rocco |
| author_sort | Sara Varanese |
| collection | DOAJ |
| description | Patients at late stage Parkinson's disease (PD) develop several motor and nonmotor complications, which dramatically impair their quality of life. These complications include motor fluctuations, dyskinesia, unpredictable or absent response to medications, falls, dysautonomia, dementia, hallucinations, sleep disorders, depression, and psychosis. The therapeutic management should be driven by the attempt to create a balance between benefit and side effects of the pharmacological treatments available. Supportive care, including physical and rehabilitative interventions, speech therapy, occupational therapy, and nursing care, has a key role in the late stage of disease.
In this review we discuss the several complications experienced by advance PD patients and their management. The importance of an integrative approach, including both pharmacological and supportive interventions, is emphasized. |
| format | Article |
| id | doaj-art-99bfe32a91364a93878b5ac6122076f5 |
| institution | Kabale University |
| issn | 2042-0080 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-99bfe32a91364a93878b5ac6122076f52025-02-03T05:59:42ZengWileyParkinson's Disease2042-00802010-01-01201010.4061/2010/480260480260Treatment of Advanced Parkinson's DiseaseSara Varanese0Zoe Birnbaum1Roger Rossi2Alessandro Di Rocco3New York University School of Medicine, Department of Neurology, Division of Movement Disorders, New York, NY 10016, USANew York University School of Medicine, Department of Neurology, Division of Movement Disorders, New York, NY 10016, USARobert Wood Johnson Medical School, Johnson Rehabilitation Institute, Edison, NJ 08818, USANew York University School of Medicine, Department of Neurology, Division of Movement Disorders, New York, NY 10016, USAPatients at late stage Parkinson's disease (PD) develop several motor and nonmotor complications, which dramatically impair their quality of life. These complications include motor fluctuations, dyskinesia, unpredictable or absent response to medications, falls, dysautonomia, dementia, hallucinations, sleep disorders, depression, and psychosis. The therapeutic management should be driven by the attempt to create a balance between benefit and side effects of the pharmacological treatments available. Supportive care, including physical and rehabilitative interventions, speech therapy, occupational therapy, and nursing care, has a key role in the late stage of disease. In this review we discuss the several complications experienced by advance PD patients and their management. The importance of an integrative approach, including both pharmacological and supportive interventions, is emphasized.http://dx.doi.org/10.4061/2010/480260 |
| spellingShingle | Sara Varanese Zoe Birnbaum Roger Rossi Alessandro Di Rocco Treatment of Advanced Parkinson's Disease Parkinson's Disease |
| title | Treatment of Advanced Parkinson's Disease |
| title_full | Treatment of Advanced Parkinson's Disease |
| title_fullStr | Treatment of Advanced Parkinson's Disease |
| title_full_unstemmed | Treatment of Advanced Parkinson's Disease |
| title_short | Treatment of Advanced Parkinson's Disease |
| title_sort | treatment of advanced parkinson s disease |
| url | http://dx.doi.org/10.4061/2010/480260 |
| work_keys_str_mv | AT saravaranese treatmentofadvancedparkinsonsdisease AT zoebirnbaum treatmentofadvancedparkinsonsdisease AT rogerrossi treatmentofadvancedparkinsonsdisease AT alessandrodirocco treatmentofadvancedparkinsonsdisease |