Liraglutide inhibits the proliferation of rat hepatic stellate cells under high glucose conditions by suppressing the ERK signaling pathway

Liraglutide inhibits the proliferation of rat hepatic stellate cells under high glucose conditions by suppressing the ERK signaling pathway

Abstract Liver fibrosis is a common complication of diabetes. Due to the crucial role of HSCs in the pathogenesis of hepatic fibrosis, they are considered a key target in anti-fibrosis research. We designed this experiment to investigate the effects of liraglutide on the proliferation of rat hepatic...

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Bibliographic Details
Main Authors: Bingge Fan, Lingbing Meng, Xiao Zheng, Lei Bai, Yaping Du, Haiyan Ding, Yu Chen, Yuna Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hepatic stellate cells
Liver fibrosis
Liraglutide
Hyperglycemia
ERK signaling pathway
Online Access:https://doi.org/10.1038/s41598-025-97872-w
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