Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital
Background: Coronavirus disease 19 (COVID-19) has become pandemic in the world with a board spectrum of clinical presentation. Secondary infection of methicillin-resistant staphylococcus aureus (MRSA) affects morbidity and mortality in patients with COVID-19. Case: We reported two COVID-19 patients...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fakultas Kedokteran, Universitas Diponegoro
2023-07-01
|
| Series: | JAI (Jurnal Anestesiologi Indonesia) |
| Subjects: | |
| Online Access: | https://ejournal.undip.ac.id/index.php/janesti/article/view/47963 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850109311460573184 |
|---|---|
| author | Dwi Retnoningrum Setyo Gundi Pramudo Taufik Eko Nugroho Qonita Nur Qolby |
| author_facet | Dwi Retnoningrum Setyo Gundi Pramudo Taufik Eko Nugroho Qonita Nur Qolby |
| author_sort | Dwi Retnoningrum |
| collection | DOAJ |
| description | Background: Coronavirus disease 19 (COVID-19) has become pandemic in the world with a board spectrum of clinical presentation. Secondary infection of methicillin-resistant staphylococcus aureus (MRSA) affects morbidity and mortality in patients with COVID-19.
Case: We reported two COVID-19 patients with MRSA hospitalized in intensive care unit (ICU) of Diponegoro National Hospital. The first patient was 61-year-old woman that was referred from another hospital with confirmed COVID-19 infection and acute respiratory distress syndrome and had been intubated. Diabetes mellitus and hypertension were known as comorbid. On day 4 of treatment in ICU, blood culture results showed MRSA infection and antibiotic therapy was replaced with Vancomycin. The patient had clinical improvement and was discharge from the hospital on the 36th day of treatment. The second one was 51-year-old woman admitted with probable COVID-19, type II Diabetes Mellitus and hypertension. On day 9th the patient was transferred to ICU because of respiratory failure, blood culture on day 15th show a result of MRSA and antibiotic therapy was replaced with vancomycin. She declined intubation procedures and died on day 20.
Discussion: Antibiotic resistance has become one of the important things in infection management in the world. Multidrug-resistant bacteria (MDR) cause treatment failure which increases the risk of death and cost. MRSA has become one of the most important MDR bacteria during the last decade causing severe infections in health facilities. Complications of bacterial infection in COVID-19, especially bacteremia increases the severity and mortality of severe patients.
Conclusion: Coinfection of MRSA in COVID-19 patients can affect the clinical outcome. One of important risk factor is history or prolonged hospitalized. Other factors are comorbidity of the patient and appropriate therapy is needed to reduce mortality in Intensive Care Unit. |
| format | Article |
| id | doaj-art-99bc2c4d4c3545d4b0ced73e8d71c64f |
| institution | OA Journals |
| issn | 2337-5124 2089-970X |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Fakultas Kedokteran, Universitas Diponegoro |
| record_format | Article |
| series | JAI (Jurnal Anestesiologi Indonesia) |
| spelling | doaj-art-99bc2c4d4c3545d4b0ced73e8d71c64f2025-08-20T02:38:06ZengFakultas Kedokteran, Universitas DiponegoroJAI (Jurnal Anestesiologi Indonesia)2337-51242089-970X2023-07-0115212913610.14710/jai.v0i0.4796322321Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National HospitalDwi Retnoningrum0https://orcid.org/0000-0003-1606-0078Setyo Gundi Pramudo1https://orcid.org/0000-0003-2120-6713Taufik Eko Nugroho2Qonita Nur Qolby3Department of Clinical Pathology, Faculty of Medicine, Universitas Diponegoro, Semarang, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Universitas Diponegoro, Semarang, IndonesiaDepartment of Anesthesiology and Intensive Theraphy, Faculty of Medicine, Diponegoro University, Semarang, IndonesiaDiponegoro National Hospital, Semarang, IndonesiaBackground: Coronavirus disease 19 (COVID-19) has become pandemic in the world with a board spectrum of clinical presentation. Secondary infection of methicillin-resistant staphylococcus aureus (MRSA) affects morbidity and mortality in patients with COVID-19. Case: We reported two COVID-19 patients with MRSA hospitalized in intensive care unit (ICU) of Diponegoro National Hospital. The first patient was 61-year-old woman that was referred from another hospital with confirmed COVID-19 infection and acute respiratory distress syndrome and had been intubated. Diabetes mellitus and hypertension were known as comorbid. On day 4 of treatment in ICU, blood culture results showed MRSA infection and antibiotic therapy was replaced with Vancomycin. The patient had clinical improvement and was discharge from the hospital on the 36th day of treatment. The second one was 51-year-old woman admitted with probable COVID-19, type II Diabetes Mellitus and hypertension. On day 9th the patient was transferred to ICU because of respiratory failure, blood culture on day 15th show a result of MRSA and antibiotic therapy was replaced with vancomycin. She declined intubation procedures and died on day 20. Discussion: Antibiotic resistance has become one of the important things in infection management in the world. Multidrug-resistant bacteria (MDR) cause treatment failure which increases the risk of death and cost. MRSA has become one of the most important MDR bacteria during the last decade causing severe infections in health facilities. Complications of bacterial infection in COVID-19, especially bacteremia increases the severity and mortality of severe patients. Conclusion: Coinfection of MRSA in COVID-19 patients can affect the clinical outcome. One of important risk factor is history or prolonged hospitalized. Other factors are comorbidity of the patient and appropriate therapy is needed to reduce mortality in Intensive Care Unit.https://ejournal.undip.ac.id/index.php/janesti/article/view/47963covid-19diabetes mellitushypertensioninfectionmethicillin-resistant staphylococcus aureus |
| spellingShingle | Dwi Retnoningrum Setyo Gundi Pramudo Taufik Eko Nugroho Qonita Nur Qolby Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital JAI (Jurnal Anestesiologi Indonesia) covid-19 diabetes mellitus hypertension infection methicillin-resistant staphylococcus aureus |
| title | Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital |
| title_full | Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital |
| title_fullStr | Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital |
| title_full_unstemmed | Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital |
| title_short | Covid-19 with Methicillin-Resistant Staphylococcus Aureus: Based on Two Cases in Diponegoro National Hospital |
| title_sort | covid 19 with methicillin resistant staphylococcus aureus based on two cases in diponegoro national hospital |
| topic | covid-19 diabetes mellitus hypertension infection methicillin-resistant staphylococcus aureus |
| url | https://ejournal.undip.ac.id/index.php/janesti/article/view/47963 |
| work_keys_str_mv | AT dwiretnoningrum covid19withmethicillinresistantstaphylococcusaureusbasedontwocasesindiponegoronationalhospital AT setyogundipramudo covid19withmethicillinresistantstaphylococcusaureusbasedontwocasesindiponegoronationalhospital AT taufikekonugroho covid19withmethicillinresistantstaphylococcusaureusbasedontwocasesindiponegoronationalhospital AT qonitanurqolby covid19withmethicillinresistantstaphylococcusaureusbasedontwocasesindiponegoronationalhospital |