Wastewater dataset on the SARS-CoV-2 sublineages circulating in Central Arkansas, USA, post-COVID-19 pandemic
Abstract The ability of coronaviruses to adapt to new hosts and cause widespread disease outbreaks poses a significant threat to global public health systems and economies. The severity of the COVID-19 pandemic has emphasized the importance of studying coronaviruses and monitoring them in communitie...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | Scientific Data |
| Online Access: | https://doi.org/10.1038/s41597-025-05100-x |
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| Summary: | Abstract The ability of coronaviruses to adapt to new hosts and cause widespread disease outbreaks poses a significant threat to global public health systems and economies. The severity of the COVID-19 pandemic has emphasized the importance of studying coronaviruses and monitoring them in communities. We investigated SARS-CoV-2 and its genomic changes in wastewater influent sampled from two metropolitan areas in Arkansas, USA, between April 2020 and March 2024. The data presented here are a follow up report to our previous publication on the findings from the period of April 2020 to January 2022 and show the SARS-CoV-2 variants circulating between February 2022 and March 2024. The levels of viral RNA were measured by reverse-transcription quantitative polymerase chain reaction and targeted three SARS-CoV-2 genes (encoding ORF1ab polyprotein, ORF1ab; surface glycoprotein, S-protein; and nucleocapsid phosphoprotein, N-protein). The identity and genetic diversity of the virus were investigated using amplicon-based RNA sequencing. These data provide important information on SARS-CoV-2 evolution and help to understand the occurrence of COVID-19 outbreaks in the community. |
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| ISSN: | 2052-4463 |