Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services

ObjectivesThis study aimed to investigate the clinical characteristics and symptoms of drug poisoning in adolescents with psychiatric conditions, and provide valuable guidance for pharmacists in the prevention and treatment of adolescent drug poisoning.MethodsA total of 84 adolescent patients with d...

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Main Authors: Yuwen Wang, Yuejing Wu, Rongda Wang, Zemin Wang, Fugang Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507639/full
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author Yuwen Wang
Yuejing Wu
Rongda Wang
Zemin Wang
Fugang Luo
author_facet Yuwen Wang
Yuejing Wu
Rongda Wang
Zemin Wang
Fugang Luo
author_sort Yuwen Wang
collection DOAJ
description ObjectivesThis study aimed to investigate the clinical characteristics and symptoms of drug poisoning in adolescents with psychiatric conditions, and provide valuable guidance for pharmacists in the prevention and treatment of adolescent drug poisoning.MethodsA total of 84 adolescent patients with drug poisoning were recruited from January 2021 to December 2023. Clinical data of drug poisoning patients were analyzed, and pharmaceutical service implications were discussed based on hospital settings and patient medication profiles.ResultsFemale adolescents constituted a higher proportion of drug poisoning cases than males. Over 50% cases involved the overdose of two or more drugs, with quantities ranging from several pills to over a hundred. The drugs most commonly involved in overdose were psychiatric medications, including antidepressants (50.0%), antipsychotics (41.7%), sedatives/hypnotics (35.7%), and mood stabilizers (26.2%). Poisoning symptoms predominantly affected the nervous system, such as dizziness, headache, drowsiness, and unsteady gait, with most patients showing improvement after symptomatic treatment (94.0%).ConclusionOur study highlights the complex relationship between psychiatric disorders and intentional drug overdose among adolescents. Effective prevention strategies, including education on poison prevention, safe medication storage, and safety planning, are crucial for reducing intentional drug overdoses in this vulnerable population.
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publisher Frontiers Media S.A.
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spelling doaj-art-99a1cad2cffe44fdb8b86d6862ce0e5e2025-08-20T02:35:56ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-07-011610.3389/fpsyt.2025.15076391507639Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy servicesYuwen Wang0Yuejing Wu1Rongda Wang2Zemin Wang3Fugang Luo4Department of Pharmacy, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Critical Care Medicine, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Pharmacy, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Pharmacy, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Critical Care Medicine, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaObjectivesThis study aimed to investigate the clinical characteristics and symptoms of drug poisoning in adolescents with psychiatric conditions, and provide valuable guidance for pharmacists in the prevention and treatment of adolescent drug poisoning.MethodsA total of 84 adolescent patients with drug poisoning were recruited from January 2021 to December 2023. Clinical data of drug poisoning patients were analyzed, and pharmaceutical service implications were discussed based on hospital settings and patient medication profiles.ResultsFemale adolescents constituted a higher proportion of drug poisoning cases than males. Over 50% cases involved the overdose of two or more drugs, with quantities ranging from several pills to over a hundred. The drugs most commonly involved in overdose were psychiatric medications, including antidepressants (50.0%), antipsychotics (41.7%), sedatives/hypnotics (35.7%), and mood stabilizers (26.2%). Poisoning symptoms predominantly affected the nervous system, such as dizziness, headache, drowsiness, and unsteady gait, with most patients showing improvement after symptomatic treatment (94.0%).ConclusionOur study highlights the complex relationship between psychiatric disorders and intentional drug overdose among adolescents. Effective prevention strategies, including education on poison prevention, safe medication storage, and safety planning, are crucial for reducing intentional drug overdoses in this vulnerable population.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507639/fulladolescentdrug poisoningpsychiatric conditionsdrug overdosepharmaceutical servicespsychiatric medications
spellingShingle Yuwen Wang
Yuejing Wu
Rongda Wang
Zemin Wang
Fugang Luo
Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
Frontiers in Psychiatry
adolescent
drug poisoning
psychiatric conditions
drug overdose
pharmaceutical services
psychiatric medications
title Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
title_full Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
title_fullStr Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
title_full_unstemmed Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
title_short Examining drug poisoning in child and adolescent psychiatric patients: clinical analysis and pharmacy services
title_sort examining drug poisoning in child and adolescent psychiatric patients clinical analysis and pharmacy services
topic adolescent
drug poisoning
psychiatric conditions
drug overdose
pharmaceutical services
psychiatric medications
url https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1507639/full
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AT yuejingwu examiningdrugpoisoninginchildandadolescentpsychiatricpatientsclinicalanalysisandpharmacyservices
AT rongdawang examiningdrugpoisoninginchildandadolescentpsychiatricpatientsclinicalanalysisandpharmacyservices
AT zeminwang examiningdrugpoisoninginchildandadolescentpsychiatricpatientsclinicalanalysisandpharmacyservices
AT fugangluo examiningdrugpoisoninginchildandadolescentpsychiatricpatientsclinicalanalysisandpharmacyservices