Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity
Piper is the largest genus of the Piperaceae family. The species of this genus have diverse biological activities and are used in pharmacopeia throughout the world. They are also used in folk medicine for treatment of many diseases in several countries including Brazil, China, India, Jamaica, and Me...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2018/5295619 |
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| author | Catia A. Almeida Mariana M. B. Azevedo Francisco C. M. Chaves Marcelo Roseo de Oliveira Igor A. Rodrigues Humberto R. Bizzo Paola E. Gama Daniela S. Alviano Celuta S. Alviano |
| author_facet | Catia A. Almeida Mariana M. B. Azevedo Francisco C. M. Chaves Marcelo Roseo de Oliveira Igor A. Rodrigues Humberto R. Bizzo Paola E. Gama Daniela S. Alviano Celuta S. Alviano |
| author_sort | Catia A. Almeida |
| collection | DOAJ |
| description | Piper is the largest genus of the Piperaceae family. The species of this genus have diverse biological activities and are used in pharmacopeia throughout the world. They are also used in folk medicine for treatment of many diseases in several countries including Brazil, China, India, Jamaica, and Mexico. In Brazil, Piper species are distributed throughout the national territory, making this genus a good candidate for biological activity screening. During our studies with Piper essential oils, we evaluated its activity against Rhizopus oryzae, the main agent of mucormycosis. The main compounds of seven Piper essential oils analyzed were Piper callosum—safrole (53.8%), P. aduncum—dillapiole (76.0%), P. hispidinervum—safrole (91.4%), P. marginatum—propiopiperone (13.2%), P. hispidum—γ-terpinene (30.9%), P. tuberculatum—(E)-caryophyllene (30.1%), and Piper sp.—linalool (14.6%). The minimum inhibitory concentration of Piper essential oils against R. oryzae ranged from 78.12 to >1250 μg/mL. The best result of total inhibition of biofilm formation was obtained with Piper sp. starting from 4.88 μg/mL. Considering the bioactive potential of EOs against planktonic cells and biofilm formation of R. oryzae could be of great interest for development of antimicrobials for therapeutic use in treatment of fungal infection. |
| format | Article |
| id | doaj-art-99a06cd0c25b403db3ed6a229ba85a39 |
| institution | OA Journals |
| issn | 1712-9532 1918-1493 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-99a06cd0c25b403db3ed6a229ba85a392025-08-20T02:18:25ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932018-01-01201810.1155/2018/52956195295619Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin ActivityCatia A. Almeida0Mariana M. B. Azevedo1Francisco C. M. Chaves2Marcelo Roseo de Oliveira3Igor A. Rodrigues4Humberto R. Bizzo5Paola E. Gama6Daniela S. Alviano7Celuta S. Alviano8Department of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (IMPG-UFRJ), CCS Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, BrazilDepartment of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (IMPG-UFRJ), CCS Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, BrazilEMBRAPA Western Amazon, Rodovia AM 10 km 29, 69010-970 Manaus, AM, BrazilEMBRAPA Western Amazon, Rodovia AM 10 km 29, 69010-970 Manaus, AM, BrazilSchool of Farmacy, Department of Natural Products and Food, Federal University of Rio de Janeiro, CCS Ilha do Fundão, 21941-902 Rio de Janeiro, RJ, BrazilEMBRAPA Food Technology, Avenida das Américas 29501, 23020-470 Rio de Janeiro, RJ, BrazilEMBRAPA Food Technology, Avenida das Américas 29501, 23020-470 Rio de Janeiro, RJ, BrazilDepartment of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (IMPG-UFRJ), CCS Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, BrazilDepartment of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro (IMPG-UFRJ), CCS Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, BrazilPiper is the largest genus of the Piperaceae family. The species of this genus have diverse biological activities and are used in pharmacopeia throughout the world. They are also used in folk medicine for treatment of many diseases in several countries including Brazil, China, India, Jamaica, and Mexico. In Brazil, Piper species are distributed throughout the national territory, making this genus a good candidate for biological activity screening. During our studies with Piper essential oils, we evaluated its activity against Rhizopus oryzae, the main agent of mucormycosis. The main compounds of seven Piper essential oils analyzed were Piper callosum—safrole (53.8%), P. aduncum—dillapiole (76.0%), P. hispidinervum—safrole (91.4%), P. marginatum—propiopiperone (13.2%), P. hispidum—γ-terpinene (30.9%), P. tuberculatum—(E)-caryophyllene (30.1%), and Piper sp.—linalool (14.6%). The minimum inhibitory concentration of Piper essential oils against R. oryzae ranged from 78.12 to >1250 μg/mL. The best result of total inhibition of biofilm formation was obtained with Piper sp. starting from 4.88 μg/mL. Considering the bioactive potential of EOs against planktonic cells and biofilm formation of R. oryzae could be of great interest for development of antimicrobials for therapeutic use in treatment of fungal infection.http://dx.doi.org/10.1155/2018/5295619 |
| spellingShingle | Catia A. Almeida Mariana M. B. Azevedo Francisco C. M. Chaves Marcelo Roseo de Oliveira Igor A. Rodrigues Humberto R. Bizzo Paola E. Gama Daniela S. Alviano Celuta S. Alviano Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity |
| title_full | Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity |
| title_fullStr | Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity |
| title_full_unstemmed | Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity |
| title_short | Piper Essential Oils Inhibit Rhizopus oryzae Growth, Biofilm Formation, and Rhizopuspepsin Activity |
| title_sort | piper essential oils inhibit rhizopus oryzae growth biofilm formation and rhizopuspepsin activity |
| url | http://dx.doi.org/10.1155/2018/5295619 |
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