Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications
Cyclodextrins (CDs) have garnered significant attention in various scientific and industrial fields due to their unique ability to form inclusion complexes with a wide range of guest molecules. This review comprehensively explores the latest advancements in cyclodextrin chemistry, focusing on the sy...
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MDPI AG
2024-11-01
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| Series: | Molecules |
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| author | Adina Magdalena Musuc |
| author_facet | Adina Magdalena Musuc |
| author_sort | Adina Magdalena Musuc |
| collection | DOAJ |
| description | Cyclodextrins (CDs) have garnered significant attention in various scientific and industrial fields due to their unique ability to form inclusion complexes with a wide range of guest molecules. This review comprehensively explores the latest advancements in cyclodextrin chemistry, focusing on the synthesis and characterization of cyclodextrin derivatives and their inclusion complexes. This review examines the biological activities of cyclodextrins, highlighting their pharmacological properties and pharmacokinetics, and discussing their promising applications in drug delivery systems. Furthermore, the industrial utilization of cyclodextrins, including their role in nanomaterials and nanostructured coatings, as well as their potential in environmental remediation, are explored. The present research also addresses the critical aspect of toxicity, particularly concerning cyclodextrin inclusion complexes, providing an overview of the current understanding and safety considerations. Through a multidisciplinary approach, the aim is to present a complete view of cyclodextrins, underscoring their versatility and impact across various domains. |
| format | Article |
| id | doaj-art-999a2efbc9e04a60b6882a7e106919d9 |
| institution | OA Journals |
| issn | 1420-3049 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-999a2efbc9e04a60b6882a7e106919d92025-08-20T01:54:08ZengMDPI AGMolecules1420-30492024-11-012922531910.3390/molecules29225319Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted ApplicationsAdina Magdalena Musuc0Institute of Physical Chemistry–Ilie Murgulescu, Romanian Academy, 202 Spl. Independentei, 060021 Bucharest, RomaniaCyclodextrins (CDs) have garnered significant attention in various scientific and industrial fields due to their unique ability to form inclusion complexes with a wide range of guest molecules. This review comprehensively explores the latest advancements in cyclodextrin chemistry, focusing on the synthesis and characterization of cyclodextrin derivatives and their inclusion complexes. This review examines the biological activities of cyclodextrins, highlighting their pharmacological properties and pharmacokinetics, and discussing their promising applications in drug delivery systems. Furthermore, the industrial utilization of cyclodextrins, including their role in nanomaterials and nanostructured coatings, as well as their potential in environmental remediation, are explored. The present research also addresses the critical aspect of toxicity, particularly concerning cyclodextrin inclusion complexes, providing an overview of the current understanding and safety considerations. Through a multidisciplinary approach, the aim is to present a complete view of cyclodextrins, underscoring their versatility and impact across various domains.https://www.mdpi.com/1420-3049/29/22/5319cyclodextrinsinclusion complexesdrug deliverypharmacokineticsnanomaterialsenvironmental remediation |
| spellingShingle | Adina Magdalena Musuc Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications Molecules cyclodextrins inclusion complexes drug delivery pharmacokinetics nanomaterials environmental remediation |
| title | Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications |
| title_full | Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications |
| title_fullStr | Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications |
| title_full_unstemmed | Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications |
| title_short | Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications |
| title_sort | cyclodextrins advances in chemistry toxicology and multifaceted applications |
| topic | cyclodextrins inclusion complexes drug delivery pharmacokinetics nanomaterials environmental remediation |
| url | https://www.mdpi.com/1420-3049/29/22/5319 |
| work_keys_str_mv | AT adinamagdalenamusuc cyclodextrinsadvancesinchemistrytoxicologyandmultifacetedapplications |