Raising the bar in ulcerative colitis management
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by growing incidence and prevalence around the world in the last few decades. The range of available existing treatment and strategies for its management is being implemented. Given the introduction of newly developed mole...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-11-01
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| Series: | Therapeutic Advances in Gastroenterology |
| Online Access: | https://doi.org/10.1177/17562848241273066 |
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| _version_ | 1850129025406599168 |
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| author | Fabrizio Fanizzi Mariangela Allocca Gionata Fiorino Alessandra Zilli Federica Furfaro Tommaso Lorenzo Parigi Laurent Peyrin-Biroulet Silvio Danese Ferdinando D’Amico |
| author_facet | Fabrizio Fanizzi Mariangela Allocca Gionata Fiorino Alessandra Zilli Federica Furfaro Tommaso Lorenzo Parigi Laurent Peyrin-Biroulet Silvio Danese Ferdinando D’Amico |
| author_sort | Fabrizio Fanizzi |
| collection | DOAJ |
| description | Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by growing incidence and prevalence around the world in the last few decades. The range of available existing treatment and strategies for its management is being implemented. Given the introduction of newly developed molecules and the lack of specific guidelines, drug positioning may represent a tough clinical challenge. UC management is mostly medical, and it has been shifting toward a more personalized approach with the aim to create a tailored strategy depending on the patient’s profile. A treat-to target strategy seems to be the best approach to reach disease control as it allows to carry out therapeutic choices based on objective and specific parameters: histological, ultrasonographic, and molecular targets may add to the already used clinical, endoscopic, and biochemical targets. In addition, dual-targeted therapy has emerged as an attractive therapeutic strategy for patients not achieving remission. This review aims to provide an overview of the available strategies to raise the bar in UC. |
| format | Article |
| id | doaj-art-9996cfbd99d643b48ed8164be1b8763b |
| institution | OA Journals |
| issn | 1756-2848 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Gastroenterology |
| spelling | doaj-art-9996cfbd99d643b48ed8164be1b8763b2025-08-20T02:33:07ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-28482024-11-011710.1177/17562848241273066Raising the bar in ulcerative colitis managementFabrizio FanizziMariangela AlloccaGionata FiorinoAlessandra ZilliFederica FurfaroTommaso Lorenzo ParigiLaurent Peyrin-BirouletSilvio DaneseFerdinando D’AmicoUlcerative colitis (UC) is a chronic inflammatory bowel disease characterized by growing incidence and prevalence around the world in the last few decades. The range of available existing treatment and strategies for its management is being implemented. Given the introduction of newly developed molecules and the lack of specific guidelines, drug positioning may represent a tough clinical challenge. UC management is mostly medical, and it has been shifting toward a more personalized approach with the aim to create a tailored strategy depending on the patient’s profile. A treat-to target strategy seems to be the best approach to reach disease control as it allows to carry out therapeutic choices based on objective and specific parameters: histological, ultrasonographic, and molecular targets may add to the already used clinical, endoscopic, and biochemical targets. In addition, dual-targeted therapy has emerged as an attractive therapeutic strategy for patients not achieving remission. This review aims to provide an overview of the available strategies to raise the bar in UC.https://doi.org/10.1177/17562848241273066 |
| spellingShingle | Fabrizio Fanizzi Mariangela Allocca Gionata Fiorino Alessandra Zilli Federica Furfaro Tommaso Lorenzo Parigi Laurent Peyrin-Biroulet Silvio Danese Ferdinando D’Amico Raising the bar in ulcerative colitis management Therapeutic Advances in Gastroenterology |
| title | Raising the bar in ulcerative colitis management |
| title_full | Raising the bar in ulcerative colitis management |
| title_fullStr | Raising the bar in ulcerative colitis management |
| title_full_unstemmed | Raising the bar in ulcerative colitis management |
| title_short | Raising the bar in ulcerative colitis management |
| title_sort | raising the bar in ulcerative colitis management |
| url | https://doi.org/10.1177/17562848241273066 |
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