A brain tumor segmentation enhancement in MRI images using U-Net and transfer learning
Abstract This paper presents a novel transfer learning approach for segmenting brain tumors in Magnetic Resonance Imaging (MRI) images. Using Fluid-Attenuated Inversion Recovery (FLAIR) abnormality segmentation masks and MRI scans from The Cancer Genome Atlas’s (TCGA’s) lower-grade glioma collection...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Medical Imaging |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12880-025-01837-4 |
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| Summary: | Abstract This paper presents a novel transfer learning approach for segmenting brain tumors in Magnetic Resonance Imaging (MRI) images. Using Fluid-Attenuated Inversion Recovery (FLAIR) abnormality segmentation masks and MRI scans from The Cancer Genome Atlas’s (TCGA’s) lower-grade glioma collection, our proposed approach uses a VGG19-based U-Net architecture with fixed pretrained weights. The experimental findings, which show an Area Under the Curve (AUC) of 0.9957, F1-Score of 0.9679, Dice Coefficient of 0.9679, Precision of 0.9541, Recall of 0.9821, and Intersection-over-Union (IoU) of 0.9378, show how effective the proposed framework is. According to these metrics, the VGG19-powered U-Net outperforms not only the conventional U-Net model but also other variants that were compared and used different pre-trained backbones in the U-Net encoder. Clinical trial registration Not applicable as this study utilized existing publicly available dataset and did not involve a clinical trial. |
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| ISSN: | 1471-2342 |