Succinate modulates oral dysbiosis and inflammation through a succinate receptor 1 dependent mechanism in aged mice
Abstract Aging involves the accumulation of various forms of molecular and cellular damage over time. Key features of aging, such as mitochondrial dysfunction, dysbiosis, and oxidative stress, are closely linked and largely driven by inflammation. This study examines the role of succinate, a key met...
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| Main Authors: | Fangxi Xu, Yuqi Guo, Scott C. Thomas, Anish Saxena, Samantha Hwang, Mridula Vardhan, Xin Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-06-01
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| Series: | International Journal of Oral Science |
| Online Access: | https://doi.org/10.1038/s41368-025-00376-6 |
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