From theory to platelets: unraveling the history and complexities of biased signaling
Abstract: Biased signaling refers to a phenomenon where a ligand preferentially activates 1 signaling pathway over another at the same receptor. It is best described for ligands that selectively activate G protein–coupled receptors through G protein or β-arrestin pathways. The concept of biased sign...
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| Main Authors: | NaShea C. Kendrick, Grace H. Huang, Germaine J. Harvey, Marvin T. Nieman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
|
| Series: | Blood Vessels, Thrombosis & Hemostasis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950327225000300 |
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