The effect of different strains of Helicobacter pylori on platelet aggregation

BACKGROUND AND AIMS: Helicobacter pylori is the major causative agent in peptic ulcer disease and is strongly implicated in the development of gastric cancer. It has also been linked, less strongly, to cardiovascular disease. The mechanisms by which certain strains of H pylori induce platelet aggreg...

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Main Authors: Paul A Corcoran, John C Atherton, Steve W Kerrigan, Torkel Wadstrom, Frank E Murray, Richard M Peek, Desmond J Fitzgerald, Dermot M Cox, Michael F Byrne
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2007/490852
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author Paul A Corcoran
John C Atherton
Steve W Kerrigan
Torkel Wadstrom
Frank E Murray
Richard M Peek
Desmond J Fitzgerald
Dermot M Cox
Michael F Byrne
author_facet Paul A Corcoran
John C Atherton
Steve W Kerrigan
Torkel Wadstrom
Frank E Murray
Richard M Peek
Desmond J Fitzgerald
Dermot M Cox
Michael F Byrne
author_sort Paul A Corcoran
collection DOAJ
description BACKGROUND AND AIMS: Helicobacter pylori is the major causative agent in peptic ulcer disease and is strongly implicated in the development of gastric cancer. It has also been linked, less strongly, to cardiovascular disease. The mechanisms by which certain strains of H pylori induce platelet aggregation through interactions with platelet glycoprotein Ib have been previously described.
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institution Kabale University
issn 0835-7900
language English
publishDate 2007-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-997c1255dab14642b0d1d934948609542025-02-03T01:29:09ZengWileyCanadian Journal of Gastroenterology0835-79002007-01-0121636737010.1155/2007/490852The effect of different strains of Helicobacter pylori on platelet aggregationPaul A Corcoran0John C Atherton1Steve W Kerrigan2Torkel Wadstrom3Frank E Murray4Richard M Peek5Desmond J Fitzgerald6Dermot M Cox7Michael F Byrne8Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, IrelandWolfson Digestive Diseases Centre and Institute of Infection, Immunity and Inflammation, University Hospital, Nottingham, UKDepartment of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, IrelandDepartment of Medical Microbiology, Dermatology and Infection, Division of Bacteriology, Lund University, Lund, SwedenDepartment of Gastroenterology, Beaumont Hospital, Dublin, IrelandDivision of Gastroenterology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USADepartment of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, IrelandDepartment of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, IrelandDepartment of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, IrelandBACKGROUND AND AIMS: Helicobacter pylori is the major causative agent in peptic ulcer disease and is strongly implicated in the development of gastric cancer. It has also been linked, less strongly, to cardiovascular disease. The mechanisms by which certain strains of H pylori induce platelet aggregation through interactions with platelet glycoprotein Ib have been previously described.http://dx.doi.org/10.1155/2007/490852
spellingShingle Paul A Corcoran
John C Atherton
Steve W Kerrigan
Torkel Wadstrom
Frank E Murray
Richard M Peek
Desmond J Fitzgerald
Dermot M Cox
Michael F Byrne
The effect of different strains of Helicobacter pylori on platelet aggregation
Canadian Journal of Gastroenterology
title The effect of different strains of Helicobacter pylori on platelet aggregation
title_full The effect of different strains of Helicobacter pylori on platelet aggregation
title_fullStr The effect of different strains of Helicobacter pylori on platelet aggregation
title_full_unstemmed The effect of different strains of Helicobacter pylori on platelet aggregation
title_short The effect of different strains of Helicobacter pylori on platelet aggregation
title_sort effect of different strains of helicobacter pylori on platelet aggregation
url http://dx.doi.org/10.1155/2007/490852
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