Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome
Lisha Li,* Junda Li,* Kai Guan Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of...
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Dove Medical Press
2024-12-01
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| Series: | Journal of Asthma and Allergy |
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| Online Access: | https://www.dovepress.com/fructose-bisphosphate-aldolase-mediating-pollen-food-allergy-syndrome-peer-reviewed-fulltext-article-JAA |
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| author | Li L Li J Guan K |
| author_facet | Li L Li J Guan K |
| author_sort | Li L |
| collection | DOAJ |
| description | Lisha Li,* Junda Li,* Kai Guan Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai Guan, Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China, Tel/Fax +86 010-69156346, Email dr_guankai@126.comAbstract: Pollen-food allergy syndrome is an IgE-mediated allergic reaction arising from cross-reactive homologous allergens found in both food and pollen. Allergens, such as pathogenesis-related protein class 10 and profilin, usually trigger oropharyngeal itching and numbness in patients, whereas lipid transfer proteins tend to induce anaphylaxis. This article presents a case study of an individual with Artemisia pollen allergy who experienced anaphylaxis after consuming red fruit ginseng, a perennial herb belonging to the Campanulaceae family. This study revealed a novel allergen component mediating cross-allergy between Artemisia pollen and food, fructose-bisphosphate aldolase, which has not been documented in the literature concerning the pollen-food allergy syndrome. Fructose-bisphosphate aldolase tends to induce anaphylaxis in patients with Artemisia pollen-allergy and warrants clinicians’ attention.Keywords: allergens, pollen-food allergy syndrome, anaphylaxis |
| format | Article |
| id | doaj-art-99794fc34d734c3c8580cf77e5bfa6c2 |
| institution | OA Journals |
| issn | 1178-6965 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Asthma and Allergy |
| spelling | doaj-art-99794fc34d734c3c8580cf77e5bfa6c22025-08-20T01:56:42ZengDove Medical PressJournal of Asthma and Allergy1178-69652024-12-01Volume 171287129098365Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy SyndromeLi LLi JGuan KLisha Li,* Junda Li,* Kai Guan Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai Guan, Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China, Tel/Fax +86 010-69156346, Email dr_guankai@126.comAbstract: Pollen-food allergy syndrome is an IgE-mediated allergic reaction arising from cross-reactive homologous allergens found in both food and pollen. Allergens, such as pathogenesis-related protein class 10 and profilin, usually trigger oropharyngeal itching and numbness in patients, whereas lipid transfer proteins tend to induce anaphylaxis. This article presents a case study of an individual with Artemisia pollen allergy who experienced anaphylaxis after consuming red fruit ginseng, a perennial herb belonging to the Campanulaceae family. This study revealed a novel allergen component mediating cross-allergy between Artemisia pollen and food, fructose-bisphosphate aldolase, which has not been documented in the literature concerning the pollen-food allergy syndrome. Fructose-bisphosphate aldolase tends to induce anaphylaxis in patients with Artemisia pollen-allergy and warrants clinicians’ attention.Keywords: allergens, pollen-food allergy syndrome, anaphylaxishttps://www.dovepress.com/fructose-bisphosphate-aldolase-mediating-pollen-food-allergy-syndrome-peer-reviewed-fulltext-article-JAAallergenspollen-food allergy syndromeanaphylaxis |
| spellingShingle | Li L Li J Guan K Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome Journal of Asthma and Allergy allergens pollen-food allergy syndrome anaphylaxis |
| title | Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome |
| title_full | Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome |
| title_fullStr | Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome |
| title_full_unstemmed | Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome |
| title_short | Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome |
| title_sort | fructose bisphosphate aldolase mediating pollen food allergy syndrome |
| topic | allergens pollen-food allergy syndrome anaphylaxis |
| url | https://www.dovepress.com/fructose-bisphosphate-aldolase-mediating-pollen-food-allergy-syndrome-peer-reviewed-fulltext-article-JAA |
| work_keys_str_mv | AT lil fructosebisphosphatealdolasemediatingpollenfoodallergysyndrome AT lij fructosebisphosphatealdolasemediatingpollenfoodallergysyndrome AT guank fructosebisphosphatealdolasemediatingpollenfoodallergysyndrome |