Therapeutic and biopharmaceutical assessment of indapamide medications

The paper is focussed on the drug release comparison for multisource indapamide medications against the original medication, Arifon retard (1,5 mg; Servier Laboratories, France). The comparative test of dissolution kinetics was performed in three media modelling physiological gastrointestinal condit...

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Main Authors: G. V. Ramenskaya, S. V. Nedogoda, I. E. Shokhin, A. Yu. Savchenko, V. S. Shlykov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 1970-01-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2071
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author G. V. Ramenskaya
S. V. Nedogoda
I. E. Shokhin
A. Yu. Savchenko
V. S. Shlykov
author_facet G. V. Ramenskaya
S. V. Nedogoda
I. E. Shokhin
A. Yu. Savchenko
V. S. Shlykov
author_sort G. V. Ramenskaya
collection DOAJ
description The paper is focussed on the drug release comparison for multisource indapamide medications against the original medication, Arifon retard (1,5 mg; Servier Laboratories, France). The comparative test of dissolution kinetics was performed in three media modelling physiological gastrointestinal conditions: hydrochloric acid solution, pH 1,2; acetate buffer, pH 4,3; and phosphate buffer, pH 6,8. The results of the dissolution kinetics test were compared to those from the comparative therapeutic studies of indapamide medications.
format Article
id doaj-art-9977aced23814d2cb1f56bf57c4ce3fe
institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 1970-01-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-9977aced23814d2cb1f56bf57c4ce3fe2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-01108981021783Therapeutic and biopharmaceutical assessment of indapamide medicationsG. V. Ramenskaya0S. V. Nedogoda1I. E. Shokhin2A. Yu. Savchenko3V. S. Shlykov4I.M. Sechenov First Moscow State Medical UniversityVolgograd State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityThe paper is focussed on the drug release comparison for multisource indapamide medications against the original medication, Arifon retard (1,5 mg; Servier Laboratories, France). The comparative test of dissolution kinetics was performed in three media modelling physiological gastrointestinal conditions: hydrochloric acid solution, pH 1,2; acetate buffer, pH 4,3; and phosphate buffer, pH 6,8. The results of the dissolution kinetics test were compared to those from the comparative therapeutic studies of indapamide medications.https://cardiovascular.elpub.ru/jour/article/view/2071dissolution testindapamidetherapeutic action
spellingShingle G. V. Ramenskaya
S. V. Nedogoda
I. E. Shokhin
A. Yu. Savchenko
V. S. Shlykov
Therapeutic and biopharmaceutical assessment of indapamide medications
Кардиоваскулярная терапия и профилактика
dissolution test
indapamide
therapeutic action
title Therapeutic and biopharmaceutical assessment of indapamide medications
title_full Therapeutic and biopharmaceutical assessment of indapamide medications
title_fullStr Therapeutic and biopharmaceutical assessment of indapamide medications
title_full_unstemmed Therapeutic and biopharmaceutical assessment of indapamide medications
title_short Therapeutic and biopharmaceutical assessment of indapamide medications
title_sort therapeutic and biopharmaceutical assessment of indapamide medications
topic dissolution test
indapamide
therapeutic action
url https://cardiovascular.elpub.ru/jour/article/view/2071
work_keys_str_mv AT gvramenskaya therapeuticandbiopharmaceuticalassessmentofindapamidemedications
AT svnedogoda therapeuticandbiopharmaceuticalassessmentofindapamidemedications
AT ieshokhin therapeuticandbiopharmaceuticalassessmentofindapamidemedications
AT ayusavchenko therapeuticandbiopharmaceuticalassessmentofindapamidemedications
AT vsshlykov therapeuticandbiopharmaceuticalassessmentofindapamidemedications