HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE

The Providencia rettgeri (P.rettgeri) is an opportunistic pathogen of human and animals and has a clinical importance as a nosocomial pathogen causing infections in the urinary system after catheterization and in immunocompromised patients less than human feces, bile and sputum. To estimati the path...

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Main Author: Zainab Ismail Ibrahim
Format: Article
Language:English
Published: College of Veterinary Medicine, University of Basrah, Iraq 2016-12-01
Series:Basrah Journal of Veterinary Research
Subjects:
Online Access:https://bjvr.uobasrah.edu.iq/article_124280_49386e8c2b7f2c4768970936f5fa3395.pdf
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author Zainab Ismail Ibrahim
author_facet Zainab Ismail Ibrahim
author_sort Zainab Ismail Ibrahim
collection DOAJ
description The Providencia rettgeri (P.rettgeri) is an opportunistic pathogen of human and animals and has a clinical importance as a nosocomial pathogen causing infections in the urinary system after catheterization and in immunocompromised patients less than human feces, bile and sputum. To estimati the pathogenic role of P.rettgeri in mice post-infection intraperitonial infection (I/P). thirty mice from both sexes, aged 6-7 weeks and weight 25-30 gm. were infected I/P by a whole bacterial suspension of P.rettgeri 0.5 ml (containing 1x108 CFU/ml), the negative control group injected I/P with (0.5 ml) PBS,five mice were sacrificed after (24, 48hrs. and 4,7 and 14 days) post-inoculation, also (n=5) were considered as negative control group, for histopathological examination. The histopathological changes at 24,48hrs until 4 days; recorded mild to moderate acute inflammatory cells reaction, edema, fibrinous exudate. At 7&14 days there was also necrosis and focal aggregation of mononuclear cells. Strong pathogenic role of P.rettegri in induction acute inflammatory response in experimental lab mice.
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spelling doaj-art-99762eefb5e046b98b1abbb9e7e8d7232025-08-20T01:50:57ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562016-12-01152102110.33762/bvetr.2016.124280124280HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICEZainab Ismail IbrahimThe Providencia rettgeri (P.rettgeri) is an opportunistic pathogen of human and animals and has a clinical importance as a nosocomial pathogen causing infections in the urinary system after catheterization and in immunocompromised patients less than human feces, bile and sputum. To estimati the pathogenic role of P.rettgeri in mice post-infection intraperitonial infection (I/P). thirty mice from both sexes, aged 6-7 weeks and weight 25-30 gm. were infected I/P by a whole bacterial suspension of P.rettgeri 0.5 ml (containing 1x108 CFU/ml), the negative control group injected I/P with (0.5 ml) PBS,five mice were sacrificed after (24, 48hrs. and 4,7 and 14 days) post-inoculation, also (n=5) were considered as negative control group, for histopathological examination. The histopathological changes at 24,48hrs until 4 days; recorded mild to moderate acute inflammatory cells reaction, edema, fibrinous exudate. At 7&14 days there was also necrosis and focal aggregation of mononuclear cells. Strong pathogenic role of P.rettegri in induction acute inflammatory response in experimental lab mice.https://bjvr.uobasrah.edu.iq/article_124280_49386e8c2b7f2c4768970936f5fa3395.pdfrettgericatheterizationbile
spellingShingle Zainab Ismail Ibrahim
HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
Basrah Journal of Veterinary Research
rettgeri
catheterization
bile
title HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
title_full HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
title_fullStr HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
title_full_unstemmed HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
title_short HISTOPATHOLOGY POST INTRAPERITONEAL INFECTION WITH Providencia rettgeri IN MICE
title_sort histopathology post intraperitoneal infection with providencia rettgeri in mice
topic rettgeri
catheterization
bile
url https://bjvr.uobasrah.edu.iq/article_124280_49386e8c2b7f2c4768970936f5fa3395.pdf
work_keys_str_mv AT zainabismailibrahim histopathologypostintraperitonealinfectionwithprovidenciarettgeriinmice