A novel mutation of ramR involved in tigecycline resistance in Klebsiella pneumoniae

A novel mutation of ramR involved in tigecycline resistance in Klebsiella pneumoniae

ABSTRACT This study aims to investigate the novel potential tigecycline resistance mechanism in Klebsiella pneumoniae and provide new insights for the clinical treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae. In vitro experiments were conducted to induce tigecycline resi...

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Bibliographic Details
Main Authors: Yuyao Xu, Qi Chen, Chenhao Zhao, Xin Ma, Lei Wang, Feinan Qian, Xiangyu Guan, Hong Du, Haifang Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
tigecycline
ramR
Klebsiella pneumoniae
resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03204-24
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