Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children

We describe a case of a 5-year-old boy who presented with multiple mild itchy and painful blisters predominantly over his trunk and limbs for one year with multiple tense bullae with hypopyon signs resulting in a half-and-half appearance of the blisters. A skin biopsy showed subepidermal separation...

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Main Authors: Susmita Pradhan, Krishna Jha, Priyanka Kumari, Shristi Shrestha, Anil Kumar Jha
Format: Article
Language:English
Published: Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) 2022-09-01
Series:Nepal Journal of Dermatology, Venereology & Leprology
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Online Access:https://nepjol.info/index.php/NJDVL/article/view/47326
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author Susmita Pradhan
Krishna Jha
Priyanka Kumari
Shristi Shrestha
Anil Kumar Jha
author_facet Susmita Pradhan
Krishna Jha
Priyanka Kumari
Shristi Shrestha
Anil Kumar Jha
author_sort Susmita Pradhan
collection DOAJ
description We describe a case of a 5-year-old boy who presented with multiple mild itchy and painful blisters predominantly over his trunk and limbs for one year with multiple tense bullae with hypopyon signs resulting in a half-and-half appearance of the blisters. A skin biopsy showed subepidermal separation with predominantly neutrophils and eosinophils in the bulla cavity and mixed infiltrate in the papillary dermis. We would like to report a case of chronic bullous disease of childhood and review its differentials for diagnostic approaches to blistering disease in children.
format Article
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institution Kabale University
issn 2091-0231
2091-167X
language English
publishDate 2022-09-01
publisher Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
record_format Article
series Nepal Journal of Dermatology, Venereology & Leprology
spelling doaj-art-99691ef260fa44debb0bb8367c6ceb042025-08-24T10:05:47ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2022-09-01202Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children Susmita Pradhan0Krishna Jha1Priyanka Kumari2Shristi Shrestha3Anil Kumar Jha4Karnali Province hospital, Surkhet NepalDepartment of Dermatology and Venereology, DI Skin Health and Referral Center P Ltd (DISHARC), Maharajgunj, Kathmandu 44600, Nepal; Department of Dermatology, Venereology, and Leprology, Rapti Academy of Health Sciences, Ghorahi, Dang, NepalKapan Hospital P Limited, Budhanilkantha-10, Kathmandu, NepalDepartment of Dermatology and Venereology, DI Skin Health and Referral Center P Ltd (DISHARC), Maharajgunj, Kathmandu 44600, Nepal; Department of Dermatology, Nepal Medical College and Teaching Hospital, Gokarneshwar, Kathmandu, NepalDepartment of Dermatology and Venereology, DI Skin Health and Referral Center P Ltd (DISHARC), Maharajgunj, Kathmandu 44600, Nepal;Department of Dermatology, Nepal Medical College and Teaching Hospital, Gokarneshwar, Kathmandu, Nepal We describe a case of a 5-year-old boy who presented with multiple mild itchy and painful blisters predominantly over his trunk and limbs for one year with multiple tense bullae with hypopyon signs resulting in a half-and-half appearance of the blisters. A skin biopsy showed subepidermal separation with predominantly neutrophils and eosinophils in the bulla cavity and mixed infiltrate in the papillary dermis. We would like to report a case of chronic bullous disease of childhood and review its differentials for diagnostic approaches to blistering disease in children. https://nepjol.info/index.php/NJDVL/article/view/47326Bullous diseaseChildrenHistopathologyImmunohistochemistry
spellingShingle Susmita Pradhan
Krishna Jha
Priyanka Kumari
Shristi Shrestha
Anil Kumar Jha
Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
Nepal Journal of Dermatology, Venereology & Leprology
Bullous disease
Children
Histopathology
Immunohistochemistry
title Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
title_full Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
title_fullStr Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
title_full_unstemmed Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
title_short Chronic Bullous Disease of Childhood: A Case Report and Review of Literature of Bullous Diseases in Children
title_sort chronic bullous disease of childhood a case report and review of literature of bullous diseases in children
topic Bullous disease
Children
Histopathology
Immunohistochemistry
url https://nepjol.info/index.php/NJDVL/article/view/47326
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AT priyankakumari chronicbullousdiseaseofchildhoodacasereportandreviewofliteratureofbullousdiseasesinchildren
AT shristishrestha chronicbullousdiseaseofchildhoodacasereportandreviewofliteratureofbullousdiseasesinchildren
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