Association between Helicobacter pylori infection and overweight or obesity in a Chinese population
Introduction: Recent studies found that Helicobacter pylori (H. pylori) infection plays a role in cardiometabolic disorders. The objective of this study was to assess the association between H. pylori infection and overweight or obesity in a Chinese population. Methodology: A cross-sectional analys...
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The Journal of Infection in Developing Countries
2015-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/6035 |
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| author | Yan Zhang Tingting Du Xi Chen Xuefeng Yu Ling Tu Cuntai Zhang |
| author_facet | Yan Zhang Tingting Du Xi Chen Xuefeng Yu Ling Tu Cuntai Zhang |
| author_sort | Yan Zhang |
| collection | DOAJ |
| description | Introduction: Recent studies found that Helicobacter pylori (H. pylori) infection plays a role in cardiometabolic disorders. The objective of this study was to assess the association between H. pylori infection and overweight or obesity in a Chinese population.
Methodology: A cross-sectional analysis using data from the subjects who underwent a health examination between January 2010 and June 2012 in the department of comprehensive medicine was performed. Diagnosis of H. pylori infection was achieved using the carbon urea breath test (14C-UBT). The participants were divided into H. pylori infection-positive group and H. pylori infection-negative group by 14C-UBT.
Results: A total of 2,050 subjects were enrolled in the study. The H. pylori infection-positive group had significantly higher body mass index (BMI) levels than did the H. pylori infection-negative group (25.32 vs 24.95, p = 0.008). There was a positive association between H. pylori infection and BMI levels (β = 0.30 ± 0.12, p = 0.015). After additional adjustment for white blood cell count (WBCC), the statistical significance disappeared (β = 0.24 ± 0.12, p = 0.053). Furthermore, a positive association between H. pylori infection and overweight/obesity according to different BMI criteria (BMI ≥ 24, BMI ≥ 23) was found. However, the association between H. pylori infection and obesity was consistently significant only based on the Asian criteria (BMI ≥ 27.5), but not significant based on the Chinese criteria (BMI ≥ 28).
Conclusion: H. pylori infection was significantly and positively associated with overweight/obesity in a Chinese population.
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| format | Article |
| id | doaj-art-996268337a604ee0b64e0dc7e748f8a8 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-996268337a604ee0b64e0dc7e748f8a82025-08-20T02:27:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-09-0190910.3855/jidc.6035Association between Helicobacter pylori infection and overweight or obesity in a Chinese populationYan Zhang0Tingting Du1Xi Chen2Xuefeng Yu3Ling Tu4Cuntai Zhang5Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, ChinaIntroduction: Recent studies found that Helicobacter pylori (H. pylori) infection plays a role in cardiometabolic disorders. The objective of this study was to assess the association between H. pylori infection and overweight or obesity in a Chinese population. Methodology: A cross-sectional analysis using data from the subjects who underwent a health examination between January 2010 and June 2012 in the department of comprehensive medicine was performed. Diagnosis of H. pylori infection was achieved using the carbon urea breath test (14C-UBT). The participants were divided into H. pylori infection-positive group and H. pylori infection-negative group by 14C-UBT. Results: A total of 2,050 subjects were enrolled in the study. The H. pylori infection-positive group had significantly higher body mass index (BMI) levels than did the H. pylori infection-negative group (25.32 vs 24.95, p = 0.008). There was a positive association between H. pylori infection and BMI levels (β = 0.30 ± 0.12, p = 0.015). After additional adjustment for white blood cell count (WBCC), the statistical significance disappeared (β = 0.24 ± 0.12, p = 0.053). Furthermore, a positive association between H. pylori infection and overweight/obesity according to different BMI criteria (BMI ≥ 24, BMI ≥ 23) was found. However, the association between H. pylori infection and obesity was consistently significant only based on the Asian criteria (BMI ≥ 27.5), but not significant based on the Chinese criteria (BMI ≥ 28). Conclusion: H. pylori infection was significantly and positively associated with overweight/obesity in a Chinese population. https://jidc.org/index.php/journal/article/view/6035Helicobacter pylori infectionbody mass indexoverweightobesity |
| spellingShingle | Yan Zhang Tingting Du Xi Chen Xuefeng Yu Ling Tu Cuntai Zhang Association between Helicobacter pylori infection and overweight or obesity in a Chinese population Journal of Infection in Developing Countries Helicobacter pylori infection body mass index overweight obesity |
| title | Association between Helicobacter pylori infection and overweight or obesity in a Chinese population |
| title_full | Association between Helicobacter pylori infection and overweight or obesity in a Chinese population |
| title_fullStr | Association between Helicobacter pylori infection and overweight or obesity in a Chinese population |
| title_full_unstemmed | Association between Helicobacter pylori infection and overweight or obesity in a Chinese population |
| title_short | Association between Helicobacter pylori infection and overweight or obesity in a Chinese population |
| title_sort | association between helicobacter pylori infection and overweight or obesity in a chinese population |
| topic | Helicobacter pylori infection body mass index overweight obesity |
| url | https://jidc.org/index.php/journal/article/view/6035 |
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