Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation
Abstract Multimodal neural interfaces open new opportunities in brain research by enabling more sophisticated and systematic neural circuit dissection. Integrating complementary features across distinct functional domains, these multifunctional neural probes have greatly advanced the interrogation o...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202406576 |
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| author | Inho Kang John Bilbily Choong Yeon Kim Chuanqian Shi Manish K. Madasu Eun Young Jeong Kyle E. Parker Do A Kwon Bum‐Joon Jung Jae‐Soon Yang Juhyun Lee Noah D.L. Kabbaj Wonhee Lee Jun‐Bo Yoon Ream Al‐Hasani Jianliang Xiao Jordan G. McCall Jae‐Woong Jeong |
| author_facet | Inho Kang John Bilbily Choong Yeon Kim Chuanqian Shi Manish K. Madasu Eun Young Jeong Kyle E. Parker Do A Kwon Bum‐Joon Jung Jae‐Soon Yang Juhyun Lee Noah D.L. Kabbaj Wonhee Lee Jun‐Bo Yoon Ream Al‐Hasani Jianliang Xiao Jordan G. McCall Jae‐Woong Jeong |
| author_sort | Inho Kang |
| collection | DOAJ |
| description | Abstract Multimodal neural interfaces open new opportunities in brain research by enabling more sophisticated and systematic neural circuit dissection. Integrating complementary features across distinct functional domains, these multifunctional neural probes have greatly advanced the interrogation of complex neural circuitry. However, introducing multiple functionalities into a compact form factor for freely behaving animals presents substantial design hurdles that complicate the device or require more than one device. Moreover, fixed functionality poses challenges in meeting the dynamic needs of chronic neuroscience inquiry, such as replacing consumable parts like batteries or drugs. To address these limitations, the modular implantable neural device (MIND) is introduced with a one‐touch magnetic assembly mechanism. Leveraging the seamless exchange of neural interface modules such as optical stimulation, drug delivery, and electrical stimulation, MIND ensures functional adaptability, reusability, and scalability. The versatile design of MIND will facilitate brain research by enabling simplified access to multiple functional modalities as needed. |
| format | Article |
| id | doaj-art-995cb0e486d944f7b3a81c926e8fef86 |
| institution | Kabale University |
| issn | 2198-3844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj-art-995cb0e486d944f7b3a81c926e8fef862025-01-29T09:50:18ZengWileyAdvanced Science2198-38442025-01-01124n/an/a10.1002/advs.202406576Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile NeuromodulationInho Kang0John Bilbily1Choong Yeon Kim2Chuanqian Shi3Manish K. Madasu4Eun Young Jeong5Kyle E. Parker6Do A Kwon7Bum‐Joon Jung8Jae‐Soon Yang9Juhyun Lee10Noah D.L. Kabbaj11Wonhee Lee12Jun‐Bo Yoon13Ream Al‐Hasani14Jianliang Xiao15Jordan G. McCall16Jae‐Woong Jeong17School of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaDepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USASchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaDepartment of Mechanical Engineering University of Colorado Boulder Boulder CO 80309 USADepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USASchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaDepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USASchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaGraduate School of Nanoscience and Technology KAIST Daejeon 34141 Republic of KoreaSchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaSchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaDepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USAGraduate School of Nanoscience and Technology KAIST Daejeon 34141 Republic of KoreaSchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaDepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USADepartment of Mechanical Engineering University of Colorado Boulder Boulder CO 80309 USADepartment of Anesthesiology Washington University in St. Louis St. Louis MO 63110 USASchool of Electrical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of KoreaAbstract Multimodal neural interfaces open new opportunities in brain research by enabling more sophisticated and systematic neural circuit dissection. Integrating complementary features across distinct functional domains, these multifunctional neural probes have greatly advanced the interrogation of complex neural circuitry. However, introducing multiple functionalities into a compact form factor for freely behaving animals presents substantial design hurdles that complicate the device or require more than one device. Moreover, fixed functionality poses challenges in meeting the dynamic needs of chronic neuroscience inquiry, such as replacing consumable parts like batteries or drugs. To address these limitations, the modular implantable neural device (MIND) is introduced with a one‐touch magnetic assembly mechanism. Leveraging the seamless exchange of neural interface modules such as optical stimulation, drug delivery, and electrical stimulation, MIND ensures functional adaptability, reusability, and scalability. The versatile design of MIND will facilitate brain research by enabling simplified access to multiple functional modalities as needed.https://doi.org/10.1002/advs.202406576magnetic assemblymodularneural deviceneuromodulationwireless |
| spellingShingle | Inho Kang John Bilbily Choong Yeon Kim Chuanqian Shi Manish K. Madasu Eun Young Jeong Kyle E. Parker Do A Kwon Bum‐Joon Jung Jae‐Soon Yang Juhyun Lee Noah D.L. Kabbaj Wonhee Lee Jun‐Bo Yoon Ream Al‐Hasani Jianliang Xiao Jordan G. McCall Jae‐Woong Jeong Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation Advanced Science magnetic assembly modular neural device neuromodulation wireless |
| title | Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation |
| title_full | Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation |
| title_fullStr | Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation |
| title_full_unstemmed | Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation |
| title_short | Wireless Modular Implantable Neural Device with One‐touch Magnetic Assembly for Versatile Neuromodulation |
| title_sort | wireless modular implantable neural device with one touch magnetic assembly for versatile neuromodulation |
| topic | magnetic assembly modular neural device neuromodulation wireless |
| url | https://doi.org/10.1002/advs.202406576 |
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