The effect of strength training on IL-6 levels and muscle fitness: an empirical study on sedentary adolescents

Introduction: The global rise in sedentary lifestyles among urban adolescents increases inflammatory markers such as interleukin-6 (IL-6) and decreases physical fitness, necessitating effective interventions. Objective: This study investigated the effects of strength training on IL-6 levels and m...

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Main Authors: Yanuar Alfan Triardhana, I Dewa Made Aryananda Wijaya Kusuma, Bayu Agung Pramono, Shery Iris Zalillah, Dewangga Yudhistira
Format: Article
Language:English
Published: FEADEF 2025-07-01
Series:Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación
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Online Access:https://revistaretos.org/index.php/retos/article/view/116177
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Summary:Introduction: The global rise in sedentary lifestyles among urban adolescents increases inflammatory markers such as interleukin-6 (IL-6) and decreases physical fitness, necessitating effective interventions. Objective: This study investigated the effects of strength training on IL-6 levels and muscular fitness in sedentary urban male adolescents. Methods: 30 male adolescents (17–20 years, 65–80 kg, 164–175 cm) participated in a pre-test-post-test control group. The treatment group participated in an 8-week strength training program (3 sessions/week, 80% 1RM, 8 repetitions, 5 sets). IL-6 levels were measured using an ELISA kit and muscular fitness was assessed using dumbbell squat tests. Data were analyzed using Wilcoxon and Mann-Whitney tests with SPSS version 25. Results: The treatment group showed a significant IL-6 reduction (p=0.027, mean difference=7.196) and improved muscular fitness (p=0.010, mean increase=4.5). The control group showed an increased IL-6 level (p=0.001, mean difference=4.835) and low muscular fitness improvement (p=0.001, mean difference=1.6). Discussion: Strength training effectively reduces inflammation and enhances fitness, consistent with prior exercise research. Conclusion: Structured strength training significantly improves IL-6 levels and muscular fitness, supporting its role in addressing adolescent sedentarism.
ISSN:1579-1726
1988-2041