Uncertainty aware domain incremental learning for cross domain depression detection

Abstract Deep learning techniques have demonstrated significant promise for detecting Major Depressive Disorder (MDD) from textual data but they still face limitations in real-world scenarios. Specifically, given the limited data availability, some efforts have resorted to aggregating data from diff...

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Main Authors: Zita Lifelo, Jianguo Ding, Huansheng Ning, Sahraoui Dhelim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10917-y
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author Zita Lifelo
Jianguo Ding
Huansheng Ning
Sahraoui Dhelim
author_facet Zita Lifelo
Jianguo Ding
Huansheng Ning
Sahraoui Dhelim
author_sort Zita Lifelo
collection DOAJ
description Abstract Deep learning techniques have demonstrated significant promise for detecting Major Depressive Disorder (MDD) from textual data but they still face limitations in real-world scenarios. Specifically, given the limited data availability, some efforts have resorted to aggregating data from different domains to expand the data volume. However, these approaches face critical challenges, including data privacy, domain gaps, class imbalance, and uncertainty arising from both the data and the model. To overcome these challenges, we propose an Uncertainty-Aware Domain Incremental Learning framework for Cross-Domain Depression Detection (UDIL-DD), integrating Uncertainty-guided Adaptive Class Threshold Learning (UACTL) and Data-Free Domain Alignment (DFDA). Specifically, our UACTL module measures the discrepancy between predictions across sequential domains and learns adaptive thresholds tailored to each class, incorporating predictive uncertainty to enhance robustness. Subsequently, the DFDA module leverages domain-similar samples identified by UACTL to approximate historical feature distributions without accessing previous domain data, effectively addressing catastrophic forgetting. To validate the effectiveness of the proposed method, we conduct extensive experiments on four benchmark MDD datasets-CMDC, DIAC-WoZ, MODMA and EATD confirming the effectiveness of our method’s potential for reliable depression detection in real-world clinical scenarios.
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spelling doaj-art-995a8e89333c450da2d95b10a950f7992025-08-20T03:04:25ZengNature PortfolioScientific Reports2045-23222025-07-0115111710.1038/s41598-025-10917-yUncertainty aware domain incremental learning for cross domain depression detectionZita Lifelo0Jianguo Ding1Huansheng Ning2Sahraoui Dhelim3School of Computer and Communications Engineering, University of Science and Technology BeijingDepartment of Computer Science, Blekinge Institute of TechnologySchool of Computer and Communications Engineering, University of Science and Technology BeijingSchool of Computing, Dublin City UniversityAbstract Deep learning techniques have demonstrated significant promise for detecting Major Depressive Disorder (MDD) from textual data but they still face limitations in real-world scenarios. Specifically, given the limited data availability, some efforts have resorted to aggregating data from different domains to expand the data volume. However, these approaches face critical challenges, including data privacy, domain gaps, class imbalance, and uncertainty arising from both the data and the model. To overcome these challenges, we propose an Uncertainty-Aware Domain Incremental Learning framework for Cross-Domain Depression Detection (UDIL-DD), integrating Uncertainty-guided Adaptive Class Threshold Learning (UACTL) and Data-Free Domain Alignment (DFDA). Specifically, our UACTL module measures the discrepancy between predictions across sequential domains and learns adaptive thresholds tailored to each class, incorporating predictive uncertainty to enhance robustness. Subsequently, the DFDA module leverages domain-similar samples identified by UACTL to approximate historical feature distributions without accessing previous domain data, effectively addressing catastrophic forgetting. To validate the effectiveness of the proposed method, we conduct extensive experiments on four benchmark MDD datasets-CMDC, DIAC-WoZ, MODMA and EATD confirming the effectiveness of our method’s potential for reliable depression detection in real-world clinical scenarios.https://doi.org/10.1038/s41598-025-10917-yMajor depressive disorderData-free domain alignmentIncremental learningClass imbalanceUncertainty estimation
spellingShingle Zita Lifelo
Jianguo Ding
Huansheng Ning
Sahraoui Dhelim
Uncertainty aware domain incremental learning for cross domain depression detection
Scientific Reports
Major depressive disorder
Data-free domain alignment
Incremental learning
Class imbalance
Uncertainty estimation
title Uncertainty aware domain incremental learning for cross domain depression detection
title_full Uncertainty aware domain incremental learning for cross domain depression detection
title_fullStr Uncertainty aware domain incremental learning for cross domain depression detection
title_full_unstemmed Uncertainty aware domain incremental learning for cross domain depression detection
title_short Uncertainty aware domain incremental learning for cross domain depression detection
title_sort uncertainty aware domain incremental learning for cross domain depression detection
topic Major depressive disorder
Data-free domain alignment
Incremental learning
Class imbalance
Uncertainty estimation
url https://doi.org/10.1038/s41598-025-10917-y
work_keys_str_mv AT zitalifelo uncertaintyawaredomainincrementallearningforcrossdomaindepressiondetection
AT jianguoding uncertaintyawaredomainincrementallearningforcrossdomaindepressiondetection
AT huanshengning uncertaintyawaredomainincrementallearningforcrossdomaindepressiondetection
AT sahraouidhelim uncertaintyawaredomainincrementallearningforcrossdomaindepressiondetection