Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds
Toll-like receptors (TLRs) play an important role in non-specific immunity against different infectious agents such as bacterium or parasite. The aim of this work was to investigate the allele and genotype frequencies of three single-nucleotide polymorphisms (SNPs) in bovine TLR1 gene in native Turk...
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Hasan Eleroğlu
2016-05-01
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| Series: | Turkish Journal of Agriculture: Food Science and Technology |
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| Online Access: | http://www.agrifoodscience.com/index.php/TURJAF/article/view/594 |
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| author | Mehmet Ulaş Çınar Korhan Arslan Esma Gamze Ilgar Bilal Akyüz |
| author_facet | Mehmet Ulaş Çınar Korhan Arslan Esma Gamze Ilgar Bilal Akyüz |
| author_sort | Mehmet Ulaş Çınar |
| collection | DOAJ |
| description | Toll-like receptors (TLRs) play an important role in non-specific immunity against different infectious agents such as bacterium or parasite. The aim of this work was to investigate the allele and genotype frequencies of three single-nucleotide polymorphisms (SNPs) in bovine TLR1 gene in native Turkish cattle breeds. DNA samples were extracted using the phenol chloroform protocol from 77 Zavot, 60 Turkish Grey, 51 East Anatolian Red, 69 Anatolian Black and 46 South Anatolian Red cattle. Target regions of the TLR1 gene were digested BsII and HpyI88III restriction enzymes. Results showed that the (A) allele frequency had higher in all native Turkish cattle breeds of the TLR1-G1409A locus. The (F) allele frequency was found to be higher compared to (E) allele in the TLR1-G1550A site. The frequencies of both (C) and (T) alleles were close to each other in the TLR1-C632T site. In conclusion genetic polymorphisms exist in Turkish native cattle populations in terms of known TLR1 variants. |
| format | Article |
| id | doaj-art-9955dcf8f004441298376da7779b4bad |
| institution | OA Journals |
| issn | 2148-127X |
| language | English |
| publishDate | 2016-05-01 |
| publisher | Hasan Eleroğlu |
| record_format | Article |
| series | Turkish Journal of Agriculture: Food Science and Technology |
| spelling | doaj-art-9955dcf8f004441298376da7779b4bad2025-08-20T02:10:17ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2016-05-014535235510.24925/turjaf.v4i5.352-355.594311Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle BreedsMehmet Ulaş Çınar0Korhan Arslan1Esma Gamze Ilgar2Bilal Akyüz3Department of Animal Science, Unit of Biometry and Genetics, Faculty of Agriculture, Erciyes University, 38039 KayseriGenetics Department, Faculty of Veterinary Medicine, Erciyes University, 38039 KayseriGenetics Department, Faculty of Veterinary Medicine, Erciyes University, 38039 KayseriGenetics Department, Faculty of Veterinary Medicine, Erciyes University, 38039 KayseriToll-like receptors (TLRs) play an important role in non-specific immunity against different infectious agents such as bacterium or parasite. The aim of this work was to investigate the allele and genotype frequencies of three single-nucleotide polymorphisms (SNPs) in bovine TLR1 gene in native Turkish cattle breeds. DNA samples were extracted using the phenol chloroform protocol from 77 Zavot, 60 Turkish Grey, 51 East Anatolian Red, 69 Anatolian Black and 46 South Anatolian Red cattle. Target regions of the TLR1 gene were digested BsII and HpyI88III restriction enzymes. Results showed that the (A) allele frequency had higher in all native Turkish cattle breeds of the TLR1-G1409A locus. The (F) allele frequency was found to be higher compared to (E) allele in the TLR1-G1550A site. The frequencies of both (C) and (T) alleles were close to each other in the TLR1-C632T site. In conclusion genetic polymorphisms exist in Turkish native cattle populations in terms of known TLR1 variants.http://www.agrifoodscience.com/index.php/TURJAF/article/view/594TLR1 geneTurkish cattle breedsAllele frequencyGenotype frequencyGenetic polymorphism |
| spellingShingle | Mehmet Ulaş Çınar Korhan Arslan Esma Gamze Ilgar Bilal Akyüz Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds Turkish Journal of Agriculture: Food Science and Technology TLR1 gene Turkish cattle breeds Allele frequency Genotype frequency Genetic polymorphism |
| title | Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds |
| title_full | Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds |
| title_fullStr | Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds |
| title_full_unstemmed | Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds |
| title_short | Determination of Toll-Like Receptor 1 Gene Polymorphisms in Zavot, Turkish Grey, East Anatolian Red, Anatolian Black and South Anatolian Red Cattle Breeds |
| title_sort | determination of toll like receptor 1 gene polymorphisms in zavot turkish grey east anatolian red anatolian black and south anatolian red cattle breeds |
| topic | TLR1 gene Turkish cattle breeds Allele frequency Genotype frequency Genetic polymorphism |
| url | http://www.agrifoodscience.com/index.php/TURJAF/article/view/594 |
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