Multi-scale modeling and simulation of skeletal muscles with different fatigue degrees based on microphysiology
Abstract The ability for skeletal muscle to constantly generate force is limited by the muscle fatigue. The calcium ion plays a significant role of the cross-bridge cycle under fatigue conditions in the force generation of skeletal muscle. To uncover complicated fatigue behavior, we conducted a mult...
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| Main Authors: | Monan Wang, Daixin Jin, Haibin Wang, Xinyi Xu, Siyuan Zheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-87443-4 |
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