Multi-scale modeling and simulation of skeletal muscles with different fatigue degrees based on microphysiology

Abstract The ability for skeletal muscle to constantly generate force is limited by the muscle fatigue. The calcium ion plays a significant role of the cross-bridge cycle under fatigue conditions in the force generation of skeletal muscle. To uncover complicated fatigue behavior, we conducted a mult...

Full description

Saved in:
Bibliographic Details
Main Authors: Monan Wang, Daixin Jin, Haibin Wang, Xinyi Xu, Siyuan Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-87443-4
Tags: Add Tag
No Tags, Be the first to tag this record!