Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer
Aims. Predicting the prognosis of gastric cancer using tumour-node-metastasis (TNM) staging is difficult as patients with the same TNM stage exhibit different prognoses. Methods. This study investigated the prognostic value of the preoperative fibrinogen/albumin ratio (FAR)-systemic inflammation res...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/3207345 |
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| author | Junbin Zhang Yongfeng Ding Weibin Wang Yimin Lu Haiyong Wang Haohao Wang Lisong Teng |
| author_facet | Junbin Zhang Yongfeng Ding Weibin Wang Yimin Lu Haiyong Wang Haohao Wang Lisong Teng |
| author_sort | Junbin Zhang |
| collection | DOAJ |
| description | Aims. Predicting the prognosis of gastric cancer using tumour-node-metastasis (TNM) staging is difficult as patients with the same TNM stage exhibit different prognoses. Methods. This study investigated the prognostic value of the preoperative fibrinogen/albumin ratio (FAR)-systemic inflammation response index (SIRI) score in resectable gastric cancer (rGC). Results. Clinicopathological features of 231 rGC patients were analysed retrospectively. Patients were divided into three groups: FAR-SIRI score 2 (FAR≥0.071 and SIRI≥0.84), 1 (FAR<0.071 and SIRI≥0.84), and 0 (SIRI<0.84). Higher FAR-SIRI scores were associated with larger tumours, poorer differentiation, and advanced TNM stage (P<0.05). Compared to those with FAR-SIRI scores of 0, patients with scores of 2 had poorer overall survival (OS). The FAR-SIRI score was an independent prognostic factor for OS in rGC. Conclusion. The present data demonstrated that FAR-SIRI scores predicted radical gastric cancer surgical outcomes and may serve as a blood marker for identifying high-risk patients. |
| format | Article |
| id | doaj-art-995050716b9c4ac6b2a2321cde7154ff |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-995050716b9c4ac6b2a2321cde7154ff2025-02-03T01:05:23ZengWileyGastroenterology Research and Practice1687-61211687-630X2020-01-01202010.1155/2020/32073453207345Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric CancerJunbin Zhang0Yongfeng Ding1Weibin Wang2Yimin Lu3Haiyong Wang4Haohao Wang5Lisong Teng6Department of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaCancer Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaDepartment of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaDepartment of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaDepartment of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaDepartment of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaDepartment of Surgical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, ChinaAims. Predicting the prognosis of gastric cancer using tumour-node-metastasis (TNM) staging is difficult as patients with the same TNM stage exhibit different prognoses. Methods. This study investigated the prognostic value of the preoperative fibrinogen/albumin ratio (FAR)-systemic inflammation response index (SIRI) score in resectable gastric cancer (rGC). Results. Clinicopathological features of 231 rGC patients were analysed retrospectively. Patients were divided into three groups: FAR-SIRI score 2 (FAR≥0.071 and SIRI≥0.84), 1 (FAR<0.071 and SIRI≥0.84), and 0 (SIRI<0.84). Higher FAR-SIRI scores were associated with larger tumours, poorer differentiation, and advanced TNM stage (P<0.05). Compared to those with FAR-SIRI scores of 0, patients with scores of 2 had poorer overall survival (OS). The FAR-SIRI score was an independent prognostic factor for OS in rGC. Conclusion. The present data demonstrated that FAR-SIRI scores predicted radical gastric cancer surgical outcomes and may serve as a blood marker for identifying high-risk patients.http://dx.doi.org/10.1155/2020/3207345 |
| spellingShingle | Junbin Zhang Yongfeng Ding Weibin Wang Yimin Lu Haiyong Wang Haohao Wang Lisong Teng Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer Gastroenterology Research and Practice |
| title | Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer |
| title_full | Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer |
| title_fullStr | Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer |
| title_full_unstemmed | Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer |
| title_short | Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer |
| title_sort | combining the fibrinogen albumin ratio and systemic inflammation response index predicts survival in resectable gastric cancer |
| url | http://dx.doi.org/10.1155/2020/3207345 |
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