Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue

Myoepithelioma is an extremely rare tumour subtype and diagnosis is based on a wide variation of cellular morphology. FNAC specimens do not always suffice for a definitive differential diagnosis which depends on histology and immunohistochemistry of the lesion. Case Presentation. A 54-year-old femal...

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Main Authors: Mario Policarpo, Valentina Longoni, Pietro Garofalo, Paolo Spina, Francesco Pia
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2016/3785979
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author Mario Policarpo
Valentina Longoni
Pietro Garofalo
Paolo Spina
Francesco Pia
author_facet Mario Policarpo
Valentina Longoni
Pietro Garofalo
Paolo Spina
Francesco Pia
author_sort Mario Policarpo
collection DOAJ
description Myoepithelioma is an extremely rare tumour subtype and diagnosis is based on a wide variation of cellular morphology. FNAC specimens do not always suffice for a definitive differential diagnosis which depends on histology and immunohistochemistry of the lesion. Case Presentation. A 54-year-old female came to our attention with dysphagia and dyslalia of 6-month standing. Ear, Nose, and Throat (ENT) examination revealed a voluminous mass on the right portion of the base of her tongue, where postcontrast T2-weighted Magnetic Resonance Imaging (MRI) evidenced a hyperintense lesion. The fine-needle aspiration specimen taken for cytology was not diagnostic, as a differential diagnosis between myoepithelioma and a malignant neoplasm of the salivary glands necessitates parameters that cytology alone cannot provide. Therefore, the whole lesion was excised by diode laser through a transoral approach. Histology and immunohistochemistry of the completely excised lesion confirmed a myoepithelioma.
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spelling doaj-art-994f3a8b67f9449f89e7f40cd22d38f02025-08-20T02:10:17ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/37859793785979Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the TongueMario Policarpo0Valentina Longoni1Pietro Garofalo2Paolo Spina3Francesco Pia4ENT Department, University of Eastern Piedmont, 28100 Novara, ItalyENT Department, University of Eastern Piedmont, 28100 Novara, ItalyENT Department, University of Eastern Piedmont, 28100 Novara, ItalyPathology Department, University of Eastern Piedmont, 28100 Novara, ItalyENT Department, University of Eastern Piedmont, 28100 Novara, ItalyMyoepithelioma is an extremely rare tumour subtype and diagnosis is based on a wide variation of cellular morphology. FNAC specimens do not always suffice for a definitive differential diagnosis which depends on histology and immunohistochemistry of the lesion. Case Presentation. A 54-year-old female came to our attention with dysphagia and dyslalia of 6-month standing. Ear, Nose, and Throat (ENT) examination revealed a voluminous mass on the right portion of the base of her tongue, where postcontrast T2-weighted Magnetic Resonance Imaging (MRI) evidenced a hyperintense lesion. The fine-needle aspiration specimen taken for cytology was not diagnostic, as a differential diagnosis between myoepithelioma and a malignant neoplasm of the salivary glands necessitates parameters that cytology alone cannot provide. Therefore, the whole lesion was excised by diode laser through a transoral approach. Histology and immunohistochemistry of the completely excised lesion confirmed a myoepithelioma.http://dx.doi.org/10.1155/2016/3785979
spellingShingle Mario Policarpo
Valentina Longoni
Pietro Garofalo
Paolo Spina
Francesco Pia
Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
Case Reports in Otolaryngology
title Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
title_full Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
title_fullStr Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
title_full_unstemmed Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
title_short Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
title_sort voluminous myoepithelioma of the minor salivary glands involving the base of the tongue
url http://dx.doi.org/10.1155/2016/3785979
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