Ammonia-induced lysosomal and mitochondrial damage: a novel perspective on T cell-based cancer immunotherapy

Ammonia-induced lysosomal and mitochondrial damage: a novel perspective on T cell-based cancer immunotherapy

Saved in:

Bibliographic Details
Main Authors:	Jianqiao Shentu, Hening Xu, Feng Zhu
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Series:	Journal of the National Cancer Center
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667005425000249
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synergistic PD‐1/LAG‐3 Inhibition: Mechanistic Insights and Implications for Enhanced Tumor Immunotherapy
by: Jianqiao Shentu, et al.
Published: (2025-06-01)

DMB-induced GSDMD-mediated pyroptosis: a novel therapeutic strategy for enhancing anti-tumor immunity
by: Jianqiao Shentu, et al.
Published: (2024-11-01)

Menin maintains lysosomal and mitochondrial homeostasis through epigenetic mechanisms in lung cancer
by: Jun-Bo Yuan, et al.
Published: (2025-03-01)

Lysosome-Mitochondrial Crosstalk in Cellular Stress and Disease
by: Szilvia Kiraly, et al.
Published: (2025-01-01)

Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells
by: Giulia Girolimetti, et al.
Published: (2025-05-01)

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells.
by: Qi Bao, et al.
Published: (2025-01-01)

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells
by: Qi Bao, et al.
Published: (2025-01-01)

Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis
by: Yuliya V Yevsyutina, et al.
Published: (2016-08-01)

Co-occurrence of AIDS and acute promyelocytic leukemia: a case report and review of the literature
by: Cheng Ai, et al.
Published: (2025-07-01)

A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy
by: Youmei Xiao, et al.
Published: (2025-02-01)

Improving ferroptosis-mediated immunotherapy for colorectal cancer through lysosome-targeted photodynamic therapy
by: Zhian Chen, et al.
Published: (2025-04-01)

Integrating mitochondrial and lysosomal gene analysis for breast cancer prognosis using machine learning
by: Huilin Chen, et al.
Published: (2025-01-01)

Corrigendum: Targeting mitochondrial damage: shining a new light on immunotherapy
by: Wenjuan Zeng, et al.
Published: (2025-03-01)

Investigating the Mechanism of IFN‐γ‐Inducible Lysosomal Thiol Reductase‐Mediated Inhibition of Breast Cancer Cell Proliferation
by: Qin Liu, et al.
Published: (2025-04-01)

Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis
by: Gabriele Civiletto, et al.
Published: (2018-10-01)

Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis
by: Mengge Chen, et al.
Published: (2020-01-01)

A Novel Method of Imaging Lysosomes in Living Human Mammary Epithelial Cells
by: Kristine Glunde, et al.
Published: (2003-01-01)

Dopamine and cortical neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction
by: Jessica Chedid, et al.
Published: (2025-06-01)

TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages
by: Guowei Xu, et al.
Published: (2025-07-01)

An active and durable ammonia cracking layer for direct ammonia protonic ceramic fuel cells
by: Liyan Chen, et al.
Published: (2024-12-01)

Dual Role of Lysosome in Cancer Development and Progression
by: Xiao-Qiong Chen, et al.
Published: (2024-11-01)

Ginsenoside Rh2 repressed the progression of prostate cancer through the mitochondrial damage induced by mitophagy and ferroptosis
by: Zhen He, et al.
Published: (2025-08-01)

PCYT2 overexpression induces mitochondrial damage and promotes apoptosis in hepatocellular carcinoma cells.
by: Xu Bei, et al.
Published: (2025-01-01)

Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI
by: Shengnan Li, et al.
Published: (2025-08-01)

Lysosomal physiology and pancreatic lysosomal stress in diabetes mellitus
by: Ling Yang, et al.
Published: (2024-09-01)

Construction of Triphenylamine-Based Aggregation-Induced Emission Luminogens for Lysosomes Imaging and Its Application in the Photodynamic Therapy of Cancer Cells
by: Zhanguo Sun, et al.
Published: (2025-05-01)

NKX3-2 Induces Ovarian Cancer Cell Migration by HDAC6-Mediated Repositioning of Lysosomes and Inhibition of Autophagy
by: Alessandra Ferraresi, et al.
Published: (2024-11-01)

Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin.
by: Ekaterina A Ivanova, et al.
Published: (2015-01-01)

Ferroptosis: a novel perspective on tumor immunotherapy
by: Yuan Xu, et al.
Published: (2025-04-01)

The awesome lysosome
by: Andrea Ballabio
Published: (2016-01-01)

Role of TFEB and TFE3 in mediating lysosomal and mitochondrial adaptations to contractile activity in skeletal muscle myotubes
by: Ashley N. Oliveira, et al.
Published: (2023-01-01)

Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation.
by: Ceri A Fielding, et al.
Published: (2014-05-01)

Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function
by: Longwei Sun, et al.
Published: (2025-01-01)

Plane Animation Simulation of the Interaction between Carbon Nanomaterials and Cell Lysosomes
by: Wen Liu, et al.
Published: (2020-01-01)

Lanthanide-specific doping in vacancy-engineered piezocatalysts induces lysosomal destruction and tumor cell pyroptosis
by: Xiaoyan Li, et al.
Published: (2025-05-01)

The ammonia-Slc4a11 axis in T cells alleviates LPS-induced mastitis
by: Yuqing Wu, et al.
Published: (2025-04-01)

Metabolic reprogramming in T cell senescence: a novel strategy for cancer immunotherapy
by: Li Liu, et al.
Published: (2025-04-01)

Lysosomal damage promotes autophagy-based unconventional secretion of the Parkinson’s disease protein PARK7
by: Biplab Kumar Dash, et al.
Published: (2024-12-01)

Lysosomes: guardians and healers within cells- multifaceted perspective and outlook from injury repair to disease treatment
by: Jianlei Bi, et al.
Published: (2025-04-01)

Singlet Oxygen-Induced Mitochondrial Reset in Cancer: A Novel Approach for Ovarian Cancer Therapy
by: Jorgelindo da Veiga Moreira, et al.
Published: (2024-11-01)