Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation

Abstract Takotsubo syndrome (TTS), also referred to as stress cardiomyopathy, is characterized by transient left ventricular apical ballooning in the absence of obstructive coronary artery disease. Catecholamine‐induced cardiac injury or vasospasm has been implicated in this pathophysiology. We pres...

Full description

Saved in:
Bibliographic Details
Main Authors: Ryo Miyake, Kisho Ohtani, Toru Hashimoto, Ryoko Yada, Tasuku Sato, Yoko Shojima, Shunji Hayashidani, Taiki Higo, Hiroyuki Tsutsui
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.12632
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832544421404475392
author Ryo Miyake
Kisho Ohtani
Toru Hashimoto
Ryoko Yada
Tasuku Sato
Yoko Shojima
Shunji Hayashidani
Taiki Higo
Hiroyuki Tsutsui
author_facet Ryo Miyake
Kisho Ohtani
Toru Hashimoto
Ryoko Yada
Tasuku Sato
Yoko Shojima
Shunji Hayashidani
Taiki Higo
Hiroyuki Tsutsui
author_sort Ryo Miyake
collection DOAJ
description Abstract Takotsubo syndrome (TTS), also referred to as stress cardiomyopathy, is characterized by transient left ventricular apical ballooning in the absence of obstructive coronary artery disease. Catecholamine‐induced cardiac injury or vasospasm has been implicated in this pathophysiology. We present a case of a 67‐year‐old man 10 years after heart transplantation diagnosed with TTS. Sympathetic reinnervation could not be detected by iodine‐123 meta iodobenzylguanidine uptake, suggesting that TTS can occur in the absence of functional sympathetic nerve systems reconstruction.
format Article
id doaj-art-994a590d9db84e3cb26eef6e33d8ff74
institution Kabale University
issn 2055-5822
language English
publishDate 2020-06-01
publisher Wiley
record_format Article
series ESC Heart Failure
spelling doaj-art-994a590d9db84e3cb26eef6e33d8ff742025-02-03T10:25:46ZengWileyESC Heart Failure2055-58222020-06-01731145114910.1002/ehf2.12632Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervationRyo Miyake0Kisho Ohtani1Toru Hashimoto2Ryoko Yada3Tasuku Sato4Yoko Shojima5Shunji Hayashidani6Taiki Higo7Hiroyuki Tsutsui8Department of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanDepartment of Cardiovascular Medicine, Faculty of Medical Sciences Kyushu University 3‐1‐1 Maidashi, Higashi‐Ku Fukuoka 812‐8582 JapanAbstract Takotsubo syndrome (TTS), also referred to as stress cardiomyopathy, is characterized by transient left ventricular apical ballooning in the absence of obstructive coronary artery disease. Catecholamine‐induced cardiac injury or vasospasm has been implicated in this pathophysiology. We present a case of a 67‐year‐old man 10 years after heart transplantation diagnosed with TTS. Sympathetic reinnervation could not be detected by iodine‐123 meta iodobenzylguanidine uptake, suggesting that TTS can occur in the absence of functional sympathetic nerve systems reconstruction.https://doi.org/10.1002/ehf2.12632Takotsubo syndromeHeart transplantationCardiac sympathetic reinnervation123I‐MIBG scintigraphy
spellingShingle Ryo Miyake
Kisho Ohtani
Toru Hashimoto
Ryoko Yada
Tasuku Sato
Yoko Shojima
Shunji Hayashidani
Taiki Higo
Hiroyuki Tsutsui
Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
ESC Heart Failure
Takotsubo syndrome
Heart transplantation
Cardiac sympathetic reinnervation
123I‐MIBG scintigraphy
title Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
title_full Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
title_fullStr Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
title_full_unstemmed Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
title_short Takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
title_sort takotsubo syndrome in a heart transplant recipient with poor cardiac sympathetic reinnervation
topic Takotsubo syndrome
Heart transplantation
Cardiac sympathetic reinnervation
123I‐MIBG scintigraphy
url https://doi.org/10.1002/ehf2.12632
work_keys_str_mv AT ryomiyake takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT kishoohtani takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT toruhashimoto takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT ryokoyada takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT tasukusato takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT yokoshojima takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT shunjihayashidani takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT taikihigo takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation
AT hiroyukitsutsui takotsubosyndromeinahearttransplantrecipientwithpoorcardiacsympatheticreinnervation