Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review

Remimazolam is a short-acting benzodiazepine that was approved by the United States Food and Drug Administration (FDA) in 2020 for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 min or less. Given its recent introduction, the use of remimazolam for ge...

Full description

Saved in:
Bibliographic Details
Main Authors: Chin Fung Kelvin Kan, Jacob E. Pollard
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/cria/7512576
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850036179628457984
author Chin Fung Kelvin Kan
Jacob E. Pollard
author_facet Chin Fung Kelvin Kan
Jacob E. Pollard
author_sort Chin Fung Kelvin Kan
collection DOAJ
description Remimazolam is a short-acting benzodiazepine that was approved by the United States Food and Drug Administration (FDA) in 2020 for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 min or less. Given its recent introduction, the use of remimazolam for general anesthesia and monitored anesthesia care (MAC) remains an area of ongoing investigation. In this report, we present the first documented case demonstrating that remimazolam can achieve hemodynamic stable burst suppression in a critically ill patient undergoing emergent craniectomy and aneurysm clipping. Additionally, this manuscript reviews the reported off-label applications of remimazolam in both the operating room and the intensive care unit (ICU) settings.
format Article
id doaj-art-99463dbcc54f4da9b7963db821aa0c97
institution DOAJ
issn 2090-6390
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Case Reports in Anesthesiology
spelling doaj-art-99463dbcc54f4da9b7963db821aa0c972025-08-20T02:57:17ZengWileyCase Reports in Anesthesiology2090-63902025-01-01202510.1155/cria/7512576Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature ReviewChin Fung Kelvin Kan0Jacob E. Pollard1Department of AnesthesiologyDepartment of AnesthesiologyRemimazolam is a short-acting benzodiazepine that was approved by the United States Food and Drug Administration (FDA) in 2020 for the induction and maintenance of procedural sedation in adults undergoing procedures lasting 30 min or less. Given its recent introduction, the use of remimazolam for general anesthesia and monitored anesthesia care (MAC) remains an area of ongoing investigation. In this report, we present the first documented case demonstrating that remimazolam can achieve hemodynamic stable burst suppression in a critically ill patient undergoing emergent craniectomy and aneurysm clipping. Additionally, this manuscript reviews the reported off-label applications of remimazolam in both the operating room and the intensive care unit (ICU) settings.http://dx.doi.org/10.1155/cria/7512576
spellingShingle Chin Fung Kelvin Kan
Jacob E. Pollard
Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
Case Reports in Anesthesiology
title Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
title_full Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
title_fullStr Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
title_full_unstemmed Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
title_short Using Remimazolam to Generate Hemodynamically Stable Burst Suppression: A Case Report and Literature Review
title_sort using remimazolam to generate hemodynamically stable burst suppression a case report and literature review
url http://dx.doi.org/10.1155/cria/7512576
work_keys_str_mv AT chinfungkelvinkan usingremimazolamtogeneratehemodynamicallystableburstsuppressionacasereportandliteraturereview
AT jacobepollard usingremimazolamtogeneratehemodynamicallystableburstsuppressionacasereportandliteraturereview