Human Umbilical Cord Mesenchymal Stem Cells Prevent Steroid-Induced Avascular Necrosis of the Femoral Head by Modulating Cellular Autophagy

Human Umbilical Cord Mesenchymal Stem Cells Prevent Steroid-Induced Avascular Necrosis of the Femoral Head by Modulating Cellular Autophagy

Background: Glucocorticoids (GCs) are critical regulatory molecules in the body, commonly utilized in clinical practice for their potent anti-inflammatory and immunosuppressive properties. However, prolonged, high-dose GC therapy is frequently associated with femoral head necrosis, a condition known...

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Bibliographic Details
Main Authors: Changheng Zhong, Hanzhe Xu, Junwen Chen, Wenxiang Cai, Jianlin Zhou, Hao Peng
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
glucocorticoid-induced osteonecrosis of femoral head
human umbilical cord mesenchymal stem cell
autophagy
core decompression
osteoblasts
Online Access:https://www.mdpi.com/2227-9059/12/12/2817
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