Recurrent Pneumothorax in a Pediatric Patient with Crohn’s Disease Receiving Ustekinumab Treatment: Case Report

Introduction: We present the case of a patient with Crohn’s disease who experienced recurrent pneumothorax after starting treatment with ustekinumab. Case Presentation: A patient with Crohn’s disease started an induction regimen with intravenous ustekinumab, and 2 months later he presente...

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Bibliographic Details
Main Authors: Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón
Format: Article
Language:English
Published: Karger Publishers 2025-03-01
Series:Case Reports in Gastroenterology
Online Access:https://karger.com/article/doi/10.1159/000543991
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Summary:Introduction: We present the case of a patient with Crohn’s disease who experienced recurrent pneumothorax after starting treatment with ustekinumab. Case Presentation: A patient with Crohn’s disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn’s disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax. Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.
ISSN:1662-0631