Enhancing Shiga toxin detection using surface plasmon resonance a study of antibody immobilization strategies

Enhancing Shiga toxin detection using surface plasmon resonance a study of antibody immobilization strategies

Abstract This study demonstrates enhanced detection of Shiga toxin (Stx), a key virulence factor in Shigella dysenteriae-induced bloody diarrhea, through optimized surface plasmon resonance (SPR) biosensor design. We present a comparative evaluation of antibody immobilization strategies, revealing s...

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Bibliographic Details
Main Authors: Zahra Karbalaee, Ali Hossein Rezayan, Ramezan Ali Taheri, Seyed Ali Mirhosseini, Mohammad Barshan-Tashnizi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
SPR
Shigella dysenteriae
Stxb
Protein G
Shiga toxin
Oriented immobilization
Online Access:https://doi.org/10.1038/s41598-025-01686-9
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