Protective role of the curcumin derivative, FM0807, in regulating JAK2/STAT3 and TGF-β1/SMAD2/3 signaling pathways in glomerular mesangial cells and renal function in db/db mice

Protective role of the curcumin derivative, FM0807, in regulating JAK2/STAT3 and TGF-β1/SMAD2/3 signaling pathways in glomerular mesangial cells and renal function in db/db mice

To determine the protective effects of FM0807 against diabetes-induced renal inflammation and fibrosis and the underlying mechanisms in vivo and in vitro . FM0807 was administered to db/db mice. Glomerular mesangial cells (HBZY-1) were cultured under high glucose conditions with or without FM0807...

Full description

Saved in:
Bibliographic Details
Main Authors: Nanwen Zhang, Duoduo Lin, Honglin Wang, Ningning Zheng, Weipeng Lai, Liangyi Li, Jianhua Xu, Xiaole Chen
Format: Article
Language:English
Published: Compuscript Ltd 2024-05-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0014
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items