ROS-activated CD147-type I interferon signaling axis drives vascular smooth muscle cell fate transition and abdominal aortic aneurysm progression
The transition of healthy contractile vascular smooth muscle cells to an inflammatory and senescent phenotype is a key driver of abdominal aortic aneurysm (AAA). Although CD147 is highly expressed in VSMCs and upregulated in aneurysmal tissue, the precise role of VSMC-derived CD147 in phenotypic swi...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-10-01
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| Series: | Redox Biology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231725002939 |
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