Bone Mass Density in HIV/AIDS Patients
Introduction. Indonesia has a high incidence of young HIV-positive population which is 20-29 years of age is in the highest group (50%). For this reason, it is important to make a better quality of life for them. Unfortunately, beside all the opportunistic infection, it was proved that osteopenia/os...
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Department of Internal Medicine, Faculty of Medicine Universitas Indonesia
2016-12-01
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| Series: | Jurnal Penyakit Dalam Indonesia |
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| Online Access: | http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/53/50 |
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| author | Nadia Ayu Mulansari Nanang Sukmana Bambang Setyohadi Siti Setiati |
| author_facet | Nadia Ayu Mulansari Nanang Sukmana Bambang Setyohadi Siti Setiati |
| author_sort | Nadia Ayu Mulansari |
| collection | DOAJ |
| description | Introduction. Indonesia has a high incidence of young HIV-positive population which is 20-29 years of age is in the highest group (50%). For this reason, it is important to make a better quality of life for them. Unfortunately, beside all the opportunistic infection, it was proved that osteopenia/osteoporosis has become a new emerging metabolic condition for HIV-infected patients. There is still no study about the description of bone mass density in HIV/AIDS patients in Indonesia.
Methods. A cross sectional study was conducted in a total of 75 HIV-seropositive antiretroviral-naïve patients. Bone mineral density (BMD) was determined by dual energy X-ray absorptiometry in lumbar spine.
Results. Seventy-five subjects had been recruited. Low BMD was found in 29.3% HIV-seropositive patients with osteopenia and 1,3% with osteoporosis. There was a higher number of osteopenia/osteoporosis in subjects who consume alcohol, smoking, lymphocyte CD4 <200 cells/mm3 and low body mass index (BMI). Duration of infection did not show any differences in both HIV with osteopenia/osteoporosis and subjects with normal bone condition.
Conclusions. Osteopenia and osteoporosis were found in patients with HIV/AIDS in RSCM with lower bone density in subjects who consumed alcohol, smoke, lymphocyte CD4 <200 cells/mm3 and low BMI. |
| format | Article |
| id | doaj-art-990dffad0fcd4cf89a57cddfc0a99b92 |
| institution | OA Journals |
| issn | 2406-8969 2549-0621 |
| language | Indonesian |
| publishDate | 2016-12-01 |
| publisher | Department of Internal Medicine, Faculty of Medicine Universitas Indonesia |
| record_format | Article |
| series | Jurnal Penyakit Dalam Indonesia |
| spelling | doaj-art-990dffad0fcd4cf89a57cddfc0a99b922025-08-20T02:01:09ZindDepartment of Internal Medicine, Faculty of Medicine Universitas IndonesiaJurnal Penyakit Dalam Indonesia2406-89692549-06212016-12-0134200205http://dx.doi.org/10.7454/jpdi.v3i4.53Bone Mass Density in HIV/AIDS PatientsNadia Ayu Mulansari0Nanang Sukmana1Bambang Setyohadi2Siti Setiati3Divisi Hematologi Onkologi Medik, Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/Rumah Sakit dr. Cipto Mangunkusumo, Jakarta IndonesiaDepartemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/Rumah Sakit dr. Cipto Mangunkusumo, Jakarta Indonesia Divisi Reumatologi, Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/Rumah Sakit dr. Cipto Mangunkusumo, Jakarta Indonesia Divisi Geriatri, Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/Rumah Sakit dr. Cipto Mangunkusumo, Jakarta Indonesia Introduction. Indonesia has a high incidence of young HIV-positive population which is 20-29 years of age is in the highest group (50%). For this reason, it is important to make a better quality of life for them. Unfortunately, beside all the opportunistic infection, it was proved that osteopenia/osteoporosis has become a new emerging metabolic condition for HIV-infected patients. There is still no study about the description of bone mass density in HIV/AIDS patients in Indonesia. Methods. A cross sectional study was conducted in a total of 75 HIV-seropositive antiretroviral-naïve patients. Bone mineral density (BMD) was determined by dual energy X-ray absorptiometry in lumbar spine. Results. Seventy-five subjects had been recruited. Low BMD was found in 29.3% HIV-seropositive patients with osteopenia and 1,3% with osteoporosis. There was a higher number of osteopenia/osteoporosis in subjects who consume alcohol, smoking, lymphocyte CD4 <200 cells/mm3 and low body mass index (BMI). Duration of infection did not show any differences in both HIV with osteopenia/osteoporosis and subjects with normal bone condition. Conclusions. Osteopenia and osteoporosis were found in patients with HIV/AIDS in RSCM with lower bone density in subjects who consumed alcohol, smoke, lymphocyte CD4 <200 cells/mm3 and low BMI.http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/53/50HIVantiretroviral naïveosteopenia/osteoporosis |
| spellingShingle | Nadia Ayu Mulansari Nanang Sukmana Bambang Setyohadi Siti Setiati Bone Mass Density in HIV/AIDS Patients Jurnal Penyakit Dalam Indonesia HIV antiretroviral naïve osteopenia/osteoporosis |
| title | Bone Mass Density in HIV/AIDS Patients |
| title_full | Bone Mass Density in HIV/AIDS Patients |
| title_fullStr | Bone Mass Density in HIV/AIDS Patients |
| title_full_unstemmed | Bone Mass Density in HIV/AIDS Patients |
| title_short | Bone Mass Density in HIV/AIDS Patients |
| title_sort | bone mass density in hiv aids patients |
| topic | HIV antiretroviral naïve osteopenia/osteoporosis |
| url | http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/53/50 |
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