Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD)
Administering fluids and drugs intravenously is crucial in caring for vulnerable patient cohorts such as critically ill patients as well as neonatal and paediatrics patient populations. Studies have revealed severe contamination of infusion solution that could be avoided by utilizing in-line filters...
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-12-01
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| Series: | Current Directions in Biomedical Engineering |
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| Online Access: | https://doi.org/10.1515/cdbme-2024-2152 |
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| _version_ | 1846096889867403264 |
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| author | Stiehm Michael Supp Laura Siewert Stefan Cherkasov Paul Reibert Jörg Forberger Dirk Schmitz Klaus-Peter |
| author_facet | Stiehm Michael Supp Laura Siewert Stefan Cherkasov Paul Reibert Jörg Forberger Dirk Schmitz Klaus-Peter |
| author_sort | Stiehm Michael |
| collection | DOAJ |
| description | Administering fluids and drugs intravenously is crucial in caring for vulnerable patient cohorts such as critically ill patients as well as neonatal and paediatrics patient populations. Studies have revealed severe contamination of infusion solution that could be avoided by utilizing in-line filters. The filtration performance consequently depends on the geometry of the filter housing. The purpose of our numerical study was to analyse the flow situation in filter housings depending on the geometry (diameter of the filter housing and distance between entrance and membrane). We compared the flow of two circular filter system with different housing width (D = 25 mm; L = 1.5 mm/3.0 mm) by means of computational fluid dynamics (CFD). The filter membrane was modelled by a porous jump condition. Both filter systems showed a highly reduced inflow on the membrane compared to the velocity in the Luer Lock ports. The wide filter housing facilitates a more homogenous inflow on the membrane (>92% of the membrane area is applied within a range of 5% of the mean velocity) compared to the narrow filter housing. Despite that difference both filter housings induced a well distributed flow through the filter membrane. However, for large filter systems (>50 mm diameter) the design of the filter housing could play a crucial role in optimising filter performance and therefore CFD should be considered. |
| format | Article |
| id | doaj-art-990c48c0ce8a4498ad116b1d6e5e64fc |
| institution | Kabale University |
| issn | 2364-5504 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj-art-990c48c0ce8a4498ad116b1d6e5e64fc2025-01-02T05:56:34ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042024-12-0110461962210.1515/cdbme-2024-2152Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD)Stiehm Michael0Supp Laura1Siewert Stefan2Cherkasov Paul3Reibert Jörg4Forberger Dirk5Schmitz Klaus-Peter6Institute for ImplantTechnology and Biomaterials e.V., Friedrich-Barnewitz-Str. 4, 18119 Rostock-Warnemünde, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyRow eMed AG –Medical 4 Life,Parchim, GermanyRow eMed AG -Medical 4 Life,Parchim, GermanyRow eMed AG -Medical 4 Life,Parchim, GermanyInstitute for ImplantTechnology and Biomaterials e.V., Rostock-Warnemünde, GermanyAdministering fluids and drugs intravenously is crucial in caring for vulnerable patient cohorts such as critically ill patients as well as neonatal and paediatrics patient populations. Studies have revealed severe contamination of infusion solution that could be avoided by utilizing in-line filters. The filtration performance consequently depends on the geometry of the filter housing. The purpose of our numerical study was to analyse the flow situation in filter housings depending on the geometry (diameter of the filter housing and distance between entrance and membrane). We compared the flow of two circular filter system with different housing width (D = 25 mm; L = 1.5 mm/3.0 mm) by means of computational fluid dynamics (CFD). The filter membrane was modelled by a porous jump condition. Both filter systems showed a highly reduced inflow on the membrane compared to the velocity in the Luer Lock ports. The wide filter housing facilitates a more homogenous inflow on the membrane (>92% of the membrane area is applied within a range of 5% of the mean velocity) compared to the narrow filter housing. Despite that difference both filter housings induced a well distributed flow through the filter membrane. However, for large filter systems (>50 mm diameter) the design of the filter housing could play a crucial role in optimising filter performance and therefore CFD should be considered.https://doi.org/10.1515/cdbme-2024-2152in-line filtercfdporous jumphomogenous flowfilter membrane |
| spellingShingle | Stiehm Michael Supp Laura Siewert Stefan Cherkasov Paul Reibert Jörg Forberger Dirk Schmitz Klaus-Peter Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) Current Directions in Biomedical Engineering in-line filter cfd porous jump homogenous flow filter membrane |
| title | Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) |
| title_full | Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) |
| title_fullStr | Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) |
| title_full_unstemmed | Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) |
| title_short | Fluid mechanical evaluation of in-line filter for fluid-handling systems by means of computational fluid dynamics (CFD) |
| title_sort | fluid mechanical evaluation of in line filter for fluid handling systems by means of computational fluid dynamics cfd |
| topic | in-line filter cfd porous jump homogenous flow filter membrane |
| url | https://doi.org/10.1515/cdbme-2024-2152 |
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