Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care
Abstract Background With Direct Acting Antivirals for Hepatitis C virus (HCV), cure is possible in > 95% including those with HIV/HCV co-infection. Achieving strategic targets for cure requires addressing barriers including suboptimal care engagement. We adapted Data to Care (D2C), a public healt...
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BMC
2025-01-01
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| Online Access: | https://doi.org/10.1186/s12913-025-12307-6 |
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| author | Maximilian Wegener Deborah Gosselin Ralph Brooks Suzanne Speers Merceditas Villanueva |
| author_facet | Maximilian Wegener Deborah Gosselin Ralph Brooks Suzanne Speers Merceditas Villanueva |
| author_sort | Maximilian Wegener |
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| description | Abstract Background With Direct Acting Antivirals for Hepatitis C virus (HCV), cure is possible in > 95% including those with HIV/HCV co-infection. Achieving strategic targets for cure requires addressing barriers including suboptimal care engagement. We adapted Data to Care (D2C), a public health strategy designed to identify and link persons out of care (OOC) for HIV, for persons with HIV/HCV co-infection untreated for HCV. Methods In partnership with Connecticut Department of Public Health (DPH), persons OOC for HIV (defined as no HIV surveillance laboratory tests from 10/1/2018–10/1/2019) were matched to a list of persons co-infected with HIV/HCV (through 12/31/2019). We used a three-phase follow-up approach (pre-work, case conferencing, and Disease Intervention Specialist (DIS) follow-up) to track outreach outcomes and re-engagement/HCV cure success. Results There were 90 HIV/HCV co-infected persons who were OOC for HIV. The pre-work and case conferencing phases determined that 33 (36.7%) had previous HCV cure or were in treatment. There were 41 eligible for DIS-follow-up of which 21 (51%) were successfully contacted and 7 (33%) successfully re-engaged (kept appointment with HCV provider). No new HCV treatment initiations were recorded. Conclusions Using a D2C approach, we identified and conducted outreach to persons who were OOC for HIV to promote HCV treatment. This approach resulted in intensive data clean-up and outreach efforts which produced modest re-engagement and no HCV treatment initiations. Future studies should develop alternative and complementary interventions to promote effective re-engagement and HCV treatment. |
| format | Article |
| id | doaj-art-9908e47163fc473a8c310fd11819df4b |
| institution | Kabale University |
| issn | 1472-6963 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Health Services Research |
| spelling | doaj-art-9908e47163fc473a8c310fd11819df4b2025-01-26T12:22:18ZengBMCBMC Health Services Research1472-69632025-01-0125111010.1186/s12913-025-12307-6Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of careMaximilian Wegener0Deborah Gosselin1Ralph Brooks2Suzanne Speers3Merceditas Villanueva4Yale School of MedicineConnecticut Department of Public HealthYale School of MedicineConnecticut Department of Public HealthYale School of MedicineAbstract Background With Direct Acting Antivirals for Hepatitis C virus (HCV), cure is possible in > 95% including those with HIV/HCV co-infection. Achieving strategic targets for cure requires addressing barriers including suboptimal care engagement. We adapted Data to Care (D2C), a public health strategy designed to identify and link persons out of care (OOC) for HIV, for persons with HIV/HCV co-infection untreated for HCV. Methods In partnership with Connecticut Department of Public Health (DPH), persons OOC for HIV (defined as no HIV surveillance laboratory tests from 10/1/2018–10/1/2019) were matched to a list of persons co-infected with HIV/HCV (through 12/31/2019). We used a three-phase follow-up approach (pre-work, case conferencing, and Disease Intervention Specialist (DIS) follow-up) to track outreach outcomes and re-engagement/HCV cure success. Results There were 90 HIV/HCV co-infected persons who were OOC for HIV. The pre-work and case conferencing phases determined that 33 (36.7%) had previous HCV cure or were in treatment. There were 41 eligible for DIS-follow-up of which 21 (51%) were successfully contacted and 7 (33%) successfully re-engaged (kept appointment with HCV provider). No new HCV treatment initiations were recorded. Conclusions Using a D2C approach, we identified and conducted outreach to persons who were OOC for HIV to promote HCV treatment. This approach resulted in intensive data clean-up and outreach efforts which produced modest re-engagement and no HCV treatment initiations. Future studies should develop alternative and complementary interventions to promote effective re-engagement and HCV treatment.https://doi.org/10.1186/s12913-025-12307-6Hepatitis C virus (HCV)HIV infectionCo-infectionOut-of-careData to care (D2C)Not in Care (NIC) |
| spellingShingle | Maximilian Wegener Deborah Gosselin Ralph Brooks Suzanne Speers Merceditas Villanueva Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care BMC Health Services Research Hepatitis C virus (HCV) HIV infection Co-infection Out-of-care Data to care (D2C) Not in Care (NIC) |
| title | Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care |
| title_full | Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care |
| title_fullStr | Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care |
| title_full_unstemmed | Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care |
| title_short | Observational pilot using a Data to Care intervention strategy to promote HCV re-engagement and cure for persons with HIV/HCV co-infection who are out of care |
| title_sort | observational pilot using a data to care intervention strategy to promote hcv re engagement and cure for persons with hiv hcv co infection who are out of care |
| topic | Hepatitis C virus (HCV) HIV infection Co-infection Out-of-care Data to care (D2C) Not in Care (NIC) |
| url | https://doi.org/10.1186/s12913-025-12307-6 |
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