Attenuation Based Quantitative Evaluation of Hepatic Steatosis Using US: Current Status and Future Perspective
Hepatic steatosis is a key characteristic of metabolic dysfunction-associated steatotic liver disease and may progress to cirrhosis and end-stage liver disease through metabolic dysfunction- associated steatohepatitis in 10%–30% of patients. Consequently, early detection and accurate assessment a...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2025-05-01
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| Series: | Journal of the Korean Society of Radiology |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2025.0024 |
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| Summary: | Hepatic steatosis is a key characteristic of metabolic dysfunction-associated steatotic liver
disease and may progress to cirrhosis and end-stage liver disease through metabolic dysfunction-
associated steatohepatitis in 10%–30% of patients. Consequently, early detection
and accurate assessment are essential. Grayscale US has traditionally been used for evaluating
hepatic steatosis; however, its limitations include reduced sensitivity for mild cases and
subjective interpretation. In addition to controlled attenuation parameter, two-dimensional
attenuation-based techniques have been recently introduced to quantify US beam attenuation
for assessing hepatic steatosis, demonstrating high diagnostic accuracy and reproducibility
while addressing some of the limitations of grayscale US. To enhance diagnostic precision
and reduce measurement variability, the standardization of examination protocols,
including measurement processes, is necessary. Additionally, further research is needed to
explore the role of a multiparametric approach combining attenuation-based techniques
with elastography in predicting disease progression. This review examines the principles, recent
research findings, and future perspectives on attenuation-based quantitative evaluation
of hepatic steatosis using US. |
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| ISSN: | 2951-0805 |