Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model

Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model

Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility among women of reproductive age, yet the range of effective treatment options remains limited. Our previous study revealed that reduced levels of nicotinamide adenine dinucleotide (NAD+) in ovarian granulosa ce...

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Bibliographic Details
Main Authors: Zhenye Zhu, Min Lei, Ruizhi Guo, Yining Xu, Yanqing Zhao, Chenlu Wei, Qingling Yang, Yingpu Sun
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Ovarian Research
Subjects:
Nicotinamide adenine dinucleotide
Nicotinamide riboside
Polycystic ovary syndrome
Ovary
Mitochondrial
Fibrosis
Online Access:https://doi.org/10.1186/s13048-025-01596-4
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